Putrescine N-methyltransferase (PMT) is the first alkaloid-specific enzyme for nicotine and tropane alkaloid formation. The pmt gene from Nicotiana tabacum was fused to the CaMV 35S promoter and integrated into the Atropa belladonna genome. Transgenic plants and derived root cultures were analysed for gene expression and for levels of alkaloids and their precursors. Scopolamine, hyoscyamine, tr...

Polyploidy is a prominent process in plant evolution and adaptation, but molecular phylogenetic studies of polyploids based on DNA sequences have often been confounded by their complex gene and genome histories. We report here a retroposon insertion in the nuclear gene granule-bound starch synthase I (GBSSI or "waxy") that clearly reveals the ancient hybrid history of the medically important po...

Introduction: Atropa belladonna (deadly nightshade) is a poisonous herb that can be especially seen in Northern regions of our country and cause anticholinergic toxic syndrome (ATS) when consumed. ATS consuming the plant which contains atropine or overdose psychoactive drugs containing (such as antipsychotics, tricyclic antidepressants). 
 Case 1: A 65-year-old female patient was admitted ...

■ ■ UPC2 method compatible with mass spectrometry for identification of unknown components IN T RODUC T ION The extract of Atropa belladonna, a perennial native to south and central Europe, North Africa, and East Asia has been used for centuries to treat a number of medical conditions, including ulcers and other gastrointestinal disorders, and pain. It is also used as an anti-muscarinic agent. ...