نتایج جستجو برای: سیاهچاله btz
تعداد نتایج: 902 فیلتر نتایج به سال:
We introduce a set of scalar fields as test fields to study the dynamical behaviors of the BTZ(Banados-Teitelboim-Zanelli) black hole. These include minimally coupled scalar, conformally coupled scalar, dilaton, and tachyon. To calculate the decay rate of the BTZ black hole, we consider both the Dirichlet boundary condition at spatial infinity and the stability condition. It turns out that the ...
The ubiquitin-proteasome system is considered to be the key regulator of protein degradation. Bortezomib (BTZ) is the first proteasome inhibitor approved by the US Food and Drug Administration for treatment of relapsed multiple myeloma and mantle cell lymphoma. Recently, BTZ treatment was reported to inhibit right ventricular hypertrophy and vascular remodeling in hypoxia-exposed and monocrotal...
Although most of the mantle cell lymphoma (MCL) patients initially responded well to bortezomib (BTZ), the dose-dependent toxicities have greatly limited the application of BTZ to MCL. To investigate the efficacy and mechanism of arsenic trioxide (ATO) with BTZ in inducing apoptosis of MCL cells, two MCL cell lines, along with primary cells from MCL patients (n = 4), were used. Additionally, th...
BTZ black hole is interpreted as exact solution of 3d higher spin gauge theory. Solutions for free massless fields in BTZ black hole background are constructed with the help of the star-product algebra formalism underlying the formulation of 3d higher spin theory. It is shown that a part of higher spin symmetries remains unbroken for special values of the BTZ parameters.
UNLABELLED BACKGROUND In clinical and experimental settings, antibody-based anti-CD20/rituximab and small molecule proteasome inhibitor (PI) bortezomib (BTZ) treatment proved effective modalities for B cell depletion in lymphoproliferative disorders as well as autoimmune diseases. However, the chronic nature of these diseases requires either prolonged or re-treatment, often with acquired res...
Prognosis of childhood acute lymphoblastic leukemia (ALL) has been dramatically improved. However, prognosis of the cases refractory to primary therapy is still poor. Recent phase 2 study on the efficacy of combination chemotherapy with bortezomib (BTZ), a proteasome inhibitor, for refractory childhood ALL demonstrated favorable clinical outcomes. However, septic death was observed in over 10% ...
The three dimensional black hole solutions of Bañados, Teitelboim and Zanelli (BTZ) are dimensionally reduced in various different ways. Solutions are obtained to the JackiwTeitelboim theory of two dimensional gravity for spinless BTZ black holes, and to a simple extension with a non-zero dilaton potential for black holes of fixed spin. Similar reductions are given for charged black holes. The ...
The purpose of this study was to determine the potential benefits of combination therapy using dimercaptosuccinic acid modified iron oxide (DMSA-Fe3O4) magnetic nanoparticles (MNPs) combined with nontoxic concentration of bortezomib (BTZ) and gambogic acid (GA) on multiple myeloma (MM) RPMI-8226 cells and possible underlying mechanisms. The effects of BTZ-GA-loaded MNP-Fe3O4 (BTZ-GA/MNPs) on ce...
Bis(benzotriazol-1-yl)phenylmethane CHPh(btz)2 and tris(benzotriazol-1-yl)methane CH(btz)3 were used as N-donor ligands to prepare luminescent heteroleptic copper(I) complexes. [Cu{CHPh(btz)2}(PPh3)2][BF4] [Cu{CHPh(btz)2}(DPEphos)][BF4] (DPEphos = bis[(2-diphenylphosphino)phenyl] ether) obtained from the corresponding borohydride complexes [Cu(BH4)(PPh3)2] [Cu(BH4)(DPEphos)] tetrafluoroboric ac...
INTRODUCTION Mantle cell lymphoma (MCL) is an incurable, often aggressive B-cell malignancy. Bortezomib (BTZ), the 20S proteasome inhibitor was originally developed and approved for treatment of relapsed refractory multiple myeloma, and subsequently approved for treatment of MCL. BTZ's single-agent activity induces clinical responses in approximately one-third of relapsed MCL patients. BTZ-cont...
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