INTRODUCTION Gestational trophoblastic disease (GTD) is a heterogeneous group of pregnancy-related disorders. Hydatidiform mole (HM) is the most common type of GTD, whereas gestational choriocarcinoma is the most aggressive. Non-receptor tyrosine kinase c-Src contributes to the transformation to a malignant phenotype in various cancers. However, the role of c-Src in the pathogenesis of GTD rema...

( Obstet Gynecol . 2021;137:355–370) Gestational trophoblastic disease (GTD) refers to rare processes originating from the placenta that require timely and appropriate management. GTD includes partial or complete hydatidiform moles (HM), as well severe gestational neoplasia (GTN) related tumors. Obstetrician-gynecologists are more likely be involved in care of women with HM who have unclear dia...

Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The most therapeutic choice is hysterectomy and it is usually successful. Here we report two cases of

BACKGROUND The aim of the study was to record the incidence of treatment for infertility prior to development of gestational trophoblastic disease (GTD). METHODS AND RESULTS A retrospective analysis was undertaken of 231 consecutive women receiving chemotherapy for persistent GTD at Weston Park Hospital, Sheffield, from 1991 to 2001. Three patients in this group had received treatment for inf...

Allen (2001) proposed the “Getting Things Done” (GTD) method for personal productivity enhancement, and reduction of the stress caused by information overload. This paper argues that recent insights in psychology and cognitive science support and extend GTD’s recommendations. We first summarize GTD with the help of a flowchart. We then review the theories of situated, embodied and distributed c...

We start by studying the Goldberger-Treiman discrepancy (GTd) ∆ = (2.259± 0.591)%. Then we look at the πN σ term, with the dimensionless ratio σN/2mN = 3.35%. Finally we return to predicting (via the quark model) the πN coupling constant, with GTd ∆ → 0 as mq → mN/3. Given the recent new value of the πNN coupling constant [1] g πNN/4π = 13.80± 0.12 or gπNN = 13.169± 0.057, (1) along with the ob...

Background Gestational trophoblastic disease (GTD) defines a heterogenenous group of interrelated lesions that arise from the trophoblastic epithelium of the placenta. There are several histologically distinct types of GTD: hydatiform mole (complete or partial), persistant/invasive gestational trophoblastic neoplasia (GTN), choriocarcinoma and placenta site trophoblastic tumors. The aim of this...

We study the performance of compressed beamforming weights feedback technique in generalized triangular decomposition (GTD) based MIMO system. GTD is a beamforming technique that enjoys QoS flexibility. The technique, however, will perform at its optimum only when the full knowledge of channel state information (CSI) is available at the transmitter. This would be impossible in the real system, ...

Myosin Va is a well known processive motor involved in transport of organelles. A tail-inhibition model is generally accepted for the regulation of myosin Va: inhibited myosin Va is in a folded conformation such that the tail domain interacts with and inhibits myosin Va motor activity. Recent studies indicate that it is the C-terminal globular tail domain (GTD) that directly inhibits the motor ...