Inactivation of luxS, encoding an AI-2 biosynthesis enzyme, in Campylobacter jejuni strain 81-176 significantly reduced colonization of the chick lower gastrointestinal tract, chemotaxis toward organic acids, and in vitro adherence to LMH chicken hepatoma cells. Thus, AI-2 production in C. jejuni contributes to host colonization and interactions with epithelial cells.

We present strong detections of methyl cyanide (CH3CN), vinyl cyanide (CH2CHCN), ethyl cyanide (CH3CH2CN) and cyanodiacetylene (HC4CN) molecules with the Green Bank Telescope (GBT) toward the Sgr B2(N) molecular cloud. Attempts to detect the corresponding isocyanide isomers were only successful in the case of methyl isocyanide (CH3NC) for its JK = 10 − 00 transition, which is the first interste...

302 Amaç: Girişimsel bronkoskopi prosedürleri havayolu lezyonlarının tanı ve tedavisinde yeni ve etkili yöntemlerdir. Özellikle endobronşiyal termal tedaviler sırasında ventilasyonun yakma tehlikesi göz önüne alındığında hava yolu yönetimi ve ventilasyon başlıca endişe konusudur. Bu çalışmanın amacı tanısal veya terapötik girişimsel bronkoskopi prosedürü uygulanan hastaların ventilasyonunda rij...

The current article tackles the challenge of reducing wastewater volumes generated from gas industry. A forward osmosis (FO) pilot unit, deployed as osmotic concentration (OC) process without draw solution (DS) recovery step, was applied an option for volume reduction real industrial effluents. commercial hollow fiber (HF) FO membrane fabricated Cellulose Triacetate (CTA) firstly tested with sy...

PURPOSE To evaluate the anatomic and functional outcomes as assessed by spectral-domain optical coherence tomography in patients with a preoperative disrupted or irregular photoreceptor inner/outer segment (IS/OS) junction who underwent idiopathic epiretinal membrane (ERM) surgery and were followed for at least 2 years. METHODS We retrospectively studied all of the patients with idiopathic ER...

Chicken xenobiotic receptor, pregnane X receptor, and constitutive androstane receptor are orphan nuclear receptors that have recently been discovered to regulate drug- and steroid-mediated induction of hepatic cytochromes P450 (CYP). This induction is part of an adaptive response involving numerous genes to exposure to drugs and chemicals and has major clinical and toxicological implications. ...

The c-MET receptor has a function in many human cancers and is a proven therapeutic target. Generating antagonistic or therapeutic monoclonal antibodies (mAbs) targeting c-MET has been difficult because bivalent, intact anti-Met antibodies frequently display agonistic activity, necessitating the use of monovalent antibody fragments for therapy. By using a novel strategy that included immunizing...

Administration of probiotic Lactobacillus cultures is an important alternative to the use of antibiotic growth promoters and has been demonstrated to improve animal health, growth performance, and preharvest food safety in poultry production. Whereas gastrointestinal colonization is thought to be critical to their probiotic functionality, factors important to Lactobacillus colonization in chick...