Parietal epithelial cell (PEC) response to glomerular injury may underlie a common pathway driving fibrogenesis following podocyte loss that typifies several glomerular disorders. Although the mammalian target of rapamycin (mTOR) pathway is important in cell homeostasis, little is known of the biological role or impact of reducing mTOR activity on PEC response following podocyte depletion, nor ...

The bone therapeutic drug zoledronate (ZOL) was loaded at and released by polyelectrolyte complex (PEC) particle films composed of either pure poly(ethyleneimine) (PEI) or maltose-modified poly(ethyleneimine) (PEI-M) and oppositely charged cellulose sulfate attached to model germanium (Ge) substrates by solution casting. Dispersions of colloidally stable polyelectrolyte complex (PEC) particles ...

Although the concept of a potential energy curve (PEC) originates from the outgrowth of the Born-Oppenheimer (BO) approximation, we propose the application of analysis methods for the physical PEC with non-Born-Oppenheimer (non-BO) wave functions. A numerical examination was performed with the highly accurate non-BO vibronic wave functions of hydrogen molecular ion, which were obtained in our p...

The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigated in vitra. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC) than normal cells. This effect could be clearly attributed to the macrophage. Vaccinia virus multiplied in PEC from normal animals while the...

BACKGROUND Agitation and aggression are common behaviors that often lead to psychiatric emergency center (PEC) admission of nursing home patients with dementia or Alzheimer's disease. However, few if any data are available that adequately describe characteristics and psychosocial triggers of agitation and aggression leading to transport and admission to a PEC. METHODS A preliminary investigat...

Solar driven water splitting can be achieved by coupling electrolyzers with PhotoVoltaics (PV). Integration of both functions in a compact PhotoElectroChemical (PEC) cell is an attractive option but presents significant scientific challenges. In this work, the design of singleand dualcompartment PEC cells for research purposes is discussed. The fabrication of separator-electrode assemblies is a...

Delamination is one of the most common defects in carbon fibre reinforced plastic (CFRP) components, such as those used in aircraft and wind turbine blades. To detect delaminations, different NDT methods such as ultrasonic (UT), eddy current (EC) scanning, flash thermography, and recent developed pulsed-eddy-current-(PEC-) simulated thermography are conducted for comparison and evaluation of th...

Treatment of recurrent sigmoid volvulus is a major challenge in frail and elderly patients with multiple co-morbidities. Early management involves endoscopic decompression with high success rate, however, its recurrence make it a real challenge as most of these patients are not suitable for major colonic resection. The aim of this study was to assess the role of percutaneous endoscopic colostom...

Polyelectrolyte complex (PEC) micelles modified with cancer cell targeting moieties were prepared for intracellular delivery of vascular endothelial growth factor (VEGF) small interfering RNA (siRNA). A luteinizing hormone-releasing hormone (LHRH) peptide analogue was coupled as a cancer targeting ligand to the distal end of the poly(ethylene glycol) (PEG)-siRNA conjugate. The siRNA-PEG-LHRH co...