OBJECTIVE Zinc deficiency is a problem world-wide. Zinc and insulin are intimately related, and a reduced zinc intake may affect glucose metabolism. The present study investigates how subclinical zinc deficiency in rats affects glucose metabolism and zinc distribution in the pancreas. METHODS Glucose metabolism was evaluated by blood-glucose, serum insulin, homeostasis model assessment (HOMA)...

in order to evaluate the efficiency of inoculation of chickpea seeds with mesorhizobium and application of nitrogen and zinc on yield and yield components of rainfed chickpea an experiment was carried out in research station of shirvan-chardavel, ilam. the experiment was conducted in randomized complete block design (rcbd) with six treatments including mesorhizobium inoculation, nitrogen (40 kg...

The role of zinc deficiency as an important cause of morbidity and impaired linear growth has prompted the need to identify indicators of population zinc status. Three indicators have been recommended - prevalence of zinc intakes below the estimated average requirement (EAR), percentage with low serum zinc concentrations, and percentage of children aged < 5 years who are stunted. This review ou...

Zinc is the second most abundant metal in human body, and a relatively large amount of zinc is found in the brain, indicating its essential role in central nerve system. Zn 2+ is stored in synaptic vesicles of glutamatergic neurons and is released from the terminals for synaptic signaling. Zinc is also found in zinc containing proteins. It is estimated that the human proteome contains about 300...

1. Abstract 2. Introduction 3. Zinc levels in normal human prostate 4. Zinc import into prostate cells 4.1. Zinc uptake transporters 4.2. Zinc import into mitochondria 5. Effects of zinc accumulation on prostate cells 5.1. Zinc and net citrate production 5.2. Zinc and terminal oxidation 5.3. Zinc effects on mitochondrial apoptogenesis 5.4. The effect of zinc on the bioenergetics of the prostate...

BACKGROUND AND OBJECTIVES This study was conducted to evaluate plasma levels of zinc in children with celiac disease, to correlate plasma zinc levels among the celiacs with short stature and diarrhea and to compare plasma zinc levels in deficient patients on gluten-free diet (GFD) with or without 4 weeks of zinc supplementation. METHODS A total of 134 patients underwent plasma zinc estimation...

Zinc plays critical roles during embryogenesis, fetal growth, and milk secretion, which increase the zinc need for pregnancy and lactation. Increased needs can be met by increasing the dietary zinc intake, along with making homeostatic adjustments in zinc utilization. Potential homeostatic adjustments include changes in circulating zinc, increased zinc absorption, decreased zinc losses, and cha...

The composition of the intestinal lumen is likely to have considerable influence upon the absorption, and consequently the nutrition and/or toxicity, of ingested zinc in aquatic environments, where zinc is both a nutrient and a toxicant of importance. The effects of amino acids upon intestinal zinc uptake in freshwater rainbow trout (Oncorhynchus mykiss) were studied using an in vivo perfusion ...

Zinc is an essential trace element that is required for the function of a large number of proteins. As these zinc-binding proteins are found within the cytosol and organelles, all eukaryotes require mechanisms to ensure that zinc is delivered to organelles, even under conditions of zinc deficiency. Although many zinc transporters belonging to the Cation Diffusion Facilitator (CDF) families have...

Among the micronutrients required by humans, zinc has particularly divergent modes of action. cDNA microarray and quantitative PCR technologies were used to investigate the zinc responsiveness of known genes that influence zinc homeostasis and to identify, through global screening, genes that may relate to phenotypic outcomes of altered dietary zinc intake. Human monocytic/macrophage THP-1 cell...