To decrease total body iodine is a key point in preparation for radioiodine study and therapy. We introduced a stringent self-managed low iodine diet (LID) and compared the outcome to that of the conventional restricted iodine diet (RID) for outpatients. We measured urine iodine to creatinine ratios (I/Cr) in patients prepared with RID for one week, LID for one week, or LID for two weeks. Mean ...

This study integrates and develops methods, namely low impact development (LID) selection method and an LID spatial planning model, to enable decision-making to minimize pluvial flooding for a community. The objective is to minimize the flood risk under the worst case of the design storm within the budget constraints. Design storms in current and future climate scenarios are analyzed as input t...

Insulin and insulin-like growth factors (IGFs) mediate a variety of signals involved in mammalian development and metabolism. To study the metabolic consequences of IGF-I deficiency, we used the liver IGF-I-deficient (LID) mouse model. The LID mice show a marked reduction (approximately 75%) in circulating IGF-I and elevated growth hormone (GH) levels. Interestingly, LID mice show a fourfold in...

purpose:  to report a patient with pretarsal dermoid cyst. patient and findings: a 2.5-year-old girl presented with a pretarsal upper lid mass and underwent excisional biopsy. a 1.0´1.0 cm cystic mass attached to upper lid tarsus was completely excised. pathologic study of the specimen revealed a dermoid cyst. conclusion: although pretarsal dermoid cyst is rare; it should be considered in all c...

BACKGROUND/AIMS Reconstruction of large full thickness upper lid defects that cannot be closed directly often rely on utilising the lower lid. An example is the Cutler Beard procedure. A one stage technique for repair of large horizontal upper lid defects utilising local posterior and anterior lamella advancement flaps is described and the results reported. METHOD Eight cases with upper lid d...

Pseudomonas aeruginosa lipase is a 29-kDa protein that, following the determination of its crystal structure, was postulated to have a lid that stretched between residues 125 and 148. In this paper, using molecular dynamics simulations, we propose that there exists, in addition to the above-mentioned lid, a novel second lid in this lipase. We further show that the second lid, covering residues ...

OBJECTIVE To investigate whether the magnitude of presynaptic dopamine depletion is a risk factor for the development of levodopa-induced dyskinesia (LID) in Parkinson disease (PD) by quantitatively analyzing (18)F-FP-CIT PET data. METHODS This retrospective cohort study enrolled a total of 127 drug-naive de novo patients with PD who completed (18)F-FP-CIT PET scanning at their initial evalua...

ANALYZING THE INTERACTIONS OF KDM5/LID AND SIN3 IN DROSOPHILAMELANOGASTERbyAMBIKAI GAJANMay 2015Advisor:Dr. Lori A. PileMajor:Biological SciencesDegree:Doctor of Philosophy SIN3, the scaffold protein of a histone modifying complex is conserved fromyeast to mammals. Drosophila SIN3 associates with both a histone deacetylase RPD3and a histone de...

H3K4me3 is a histone modification that accumulates at the transcription-start site (TSS) of active genes and is known to be important for transcription activation. The way in which H3K4me3 is regulated at TSS and the actual molecular basis of its contribution to transcription remain largely unanswered. To address these questions, we have analyzed the contribution of dKDM5/LID, the main H3K4me3 ...

BACKGROUND It is unclear whether patients with different clinical subtypes of Parkinson disease (PD) differ in their risk of developing levodopa-induced dyskinesia (LID) and whether resting tremor is negatively correlated with this risk. OBJECTIVES To determine whether resting tremor as an initial manifestation of PD negatively correlated with subsequent occurrence and severity of LID and to ...