WHEN it was observed that the majority of SD-identical unrelated individuals stimulated each other in the MLC test, it was postulated in agreement with earlier suggestions by others that MLC activation might be coded by a locus separate from the LA and Four loci." The existence of such a MLC locus is now generally accepted.^About 10% of the MLC tests between SD-identical unrelated persons are n...

We report the presence of Mlc in a thermophilic bacterium. Mlc is known as a global regulator of sugar metabolism in gram-negative enteric bacteria that is controlled by sequestration to a glucose-transporting EII(Glc) of the phosphotransferase system (PTS). Since thermophilic bacteria do not possess PTS, Mlc in Thermus thermophilus must be differently controlled. DNA sequence alignments betwee...

megalencephalic leukoencephalopathy with subcortical cysts (mlc) is an autosomal recessive disorder characterized by macrocephaly and a slowly progressive clinical course marked by ataxia, spasticity and mental decline. mlc is caused by mutations in the gene mlc1 which encodes a novel protein, mlc1. here we report 4 cases presenting with macrocephaly, spasticity, ataxia and abnormal cerebral wh...

introduction: this study compared apical dye penetration using lateral condensation technique (lc) and lc technique with a reciprocal handpiece (mechanical lateral condensation or mlc) as a new method. materials and methods: forty-eight human extracted straight canine teeth were used. after crown amputation, the teeth were randomly divided into four experimental groups of 10 teeth each and two ...

Quality assurance (QA) of the multileaf collimator (MLC) is a critical step for the delivery of intensity modulated radiation therapy treatment plan. While QA procedures for motor-driven MLC have been published extensively, those for binary MLCs such as the one used for helical tomotherapy have not been presented in the literature, as this is still a fairly new technology. In this study, seven ...

Mlc is a global regulator of carbohydrate metabolism. Recent studies have revealed that Mlc is depressed by protein-protein interaction with enzyme IICB(Glc), a glucose-specific permease, which is encoded by ptsG. The mlc gene has been previously known to be transcribed by two promoters, P1(+1) and P2(+13), and have a binding site of its own gene product at +16. However, the mechanism of transc...

Background: Radiotherapy with large mantle field is an effective technique in increasing the risk of secondary cancers among HL (Hodgkin Lymphoma) patients; therefore, it is essential to choose an effective treatment field including the least medical conditions in radiotherapy.Objective: The present study aimed to plan separate fields for neck and mediastinum using various energies, to compare ...

A new approach for the inverse treatment planning in radiation therapy with the multileaf colli-mator (MLC) technique is presented. The application of the MLC-techniques requires an algorithm for the computation of the positions or velocities of leaves as a function of time such that the prescribed dose in the patient space is obtained. First the intensity distribution in the treatment space is...