B. Turkbey, H. Mani, M. Bernardo, Y. Pang, K. Khurana, P. Albert, P. Pinto, M. Merino, and P. L. Choyke Molecular Imaging Program, NCI, NIH, Bethesda, MD, United States, Laboratory of Pathology, NCI, NIH, Bethesda, MD, United States, Philips Healthcare, Bethesda, MD, United States, Urologic Oncology Branch, NCI, NIH, Bethesda, MD, United States, Biometric Research Branch, Division of Cancer Tre...

The newly synthesized naftopidil analogue HUHS1015 reduced cell viability in malignant pleural mesothelioma cell lines MSTO-211H, NCI-H28, NCI-H2052, and NCI-H2452, with the potential greater than that for the anticancer drugs paclitaxel or cisplatin at concentrations higher than 30 μM. HUHS1015 induced both necrosis and apoptosis of MSTO-211H and NCI-H2052 cells. HUHS1015 upregulated expressio...

Abstract The International Council of Management Consulting Institutes (ICMCI) National Index (NCI) project was initiated in 2017. aims to identify the key conditions which help explain relative strength a country’s management consulting sector, and use these data provide reasonable estimates any sector ($m) where this is not known. paper has two parts. first shows numerical using NCI formula f...

In the previous study fifteen jatrophane diterpenes were isolated from Euphorbia nicaeensis latex. Fourteen of them have been shown to be potent P-glycoprotein (P-gp) inhibitor in two MDR cancer cells (NCI-H460/R and DLD1-TxR). The aim this was determine whether which can root plant, then examine their inhibition power on selected cell lines (NCI- -H460, DLD1, U87, NCI-H460/R, DLD1-TxR U87-TxR)...

Osimertinib (OSI, also known as AZD9291) is the newest FDA-approved epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor for non-small cell lung cancer (NSCLC) patients with EGFR T790M mutation. However, resistance to OSI is likely to progress and the study of potential OSI-resistant mechanisms in advanced is necessary. Here, the OSI-resistant NCI-H1975/OSIR cells were established....

هدف: هدف پژوهش حاضر، ساخت و اعتبار­سنجی سیاهه آسیب‌شناسی روانشناختی نوجوانان در فضای مجازی بود. روش: روش آمیخته اکتشافی (کیفی-کمی) بدین منظور با استفاده از تحلیل مضمون مقالات مصاحبه‌های انجام‌شده متخصصان فعال مجازی، آسیب­ ها شناسایی شدند بر اساس آن ­ای ساخته شد. جامعه آماری بخش کیفی شامل مقالات، اساتید دانشگاه­ های اراک، اصفهان، امام خمینی قزوین شهر اراک بودند که نمونه هدفمند آنها انتخاب کمی بو...

Background: Small cell lung cancer (SCLC) is a highly aggressive and lethal tumor. Rapid response to chemotherapy radiotherapy observed in the majority of patients, but most them relapse within 6 12 months. Despite recent addition immunotherapy front-line chemotherapy, improvements progression-free overall survival are modest, with deaths occurring year diagnosis. SCLC heterogeneous can be divi...