The relationship between c-erbB-2 gene expression (assessed immunohistochemically), S-phase fraction (SPF) and prognosis has been analysed in 172 women with primary breast cancer. c-erbB-2 staining was independent of age, tumour size, number of nodes involved, tumour grade and DNA ploidy, but was more common in oestrogen receptor (ER) negative tumours (P = 0.02) and progesterone receptor (PgR) ...

Spirulina platensis (SP) is a blue-green microalga that has recently raised attention not only as a nutritional component, but also as a source of bioactivities that have therapeutic effects and may find application in medicine, including cancer treatment. In the present study we determined the cytotoxic effect of S. platensis filtrates (SPF) on human colon cancer cell line Caco-2. Three concen...

Replacement boars and gilts are potential carriers of infectious agents for pig production farms. Demand for healthy breeding stock is increasing. Consequently, production facilities of these animals should be of high health. However, from a genetic point of view questions should be raised whether 1) genetic trend realized under high health conditions (SPF) will be expressed in the same magnitu...

SPF-eggs are used for the production and control of vaccines for humans and animals. This presentation describes the major areas in which embryonated SPF-eggs are used. Furthermore, the advantages and disadvantages of using these eggs in production and control of vaccines will be discussed in comparison to conventional eggs on the one hand and cell lines which are derived from SPF-eggs on the o...

BACKGROUND Packing after closed reduction of nasal fracture causes uncomfortable nasal obstruction in patients. We packed the superior meatus with synthetic polyurethane foam (SPF) to support the nasal bone, and packed the middle nasal meatus with a nasal airway splint (NAS) and SPF. The aim of this article is prospectively to compare the subjective patient discomfort of SPF (Nasopore Forte plu...

Previously our novel Shared Potential Field (SPF) method has been introduced and compared against a non-sharing control in both simulation and laboratory settings. In this paper, we compare the SPF against an existing type of robot architecture, a hybrid robotic system. The task given to the multi-robot systems is to traverse an unknown environment, in search of a single target. The metric of p...

Superplastic forming (SPF) is conducted in a heated, pressurized die where direct monitoring of critical SPF parameters is extremely difficult. Numerical models provide a critical means of tracking the forming process, allowing the applied gas pressure to be adjusted to maintain optimum SPF behavior throughout the forming process. This paper describes how the MARC finite element code was used t...

OBJECTIVE We investigated the correlation between ploidy or S-phase fraction (SPF) and the clinical pathological characteristics of patients with peritoneal carcinomatosis from ovarian cancer. We also assessed their relation with the in vivo and in vitro response to several chemotherapeutic agents. PATIENTS AND METHODS Fifty-three patients with peritoneal carcinomatosis from ovarian cancer we...