The mechanism of the post-translational modulation of nitrate reductase activity (NR, EC 1.6.6.1) is briefly summarized, and it is shown that by this mechanism nitric oxide production through NR is also rapidly modulated. New and partly unexpected details on the modulation mechanism have been obtained by using immunological techniques. The phosphorylation state of NR has been assessed with pept...

Seite 8 Geschichten von: Luftschiffen Festivals Skibrillen Schnitzeljagden und Herrn Kortum ...der Forschung 1995 Die Initiative zur Einrichtung eines Tages der Forschung kam im Jahr 1994 von den Spitzenverbänden der Industrie, die hiermit zur Verbesserung des Innovationsklimas in Deutschland beitragen wollten. Hochschulrektorenkonferenz und Deutsche Forschungsgemeinschaft griffen die Idee auf ...

“Tue Gutes und rede darüber”, lautet der Leitsatz der Öffentlichkeitsarbeit. Wer Gutes tut, der erwartet zumeist Anerkennung für seine Taten. Damit ist aber längst nicht entschieden, ob allein öffentliches Lob der Antrieb guter Taten ist wie überhaupt es mit öffentlichem Lob seine eigene Bewandtnis hat. Von Kindesbeinen an lernen wir (noch?), uns zu bedanken, wenn uns Gutes widerfährt. Unser hö...

If you take meetings, instant messaging, emails and calls out of your working day there is a fair chance that the remaining work-related communication is relatively small. Most of people’s daily lives is interacting with the social network at the office, engaging with people and using relationships to drive innovation and results. Most individuals would attest to having a good understanding of ...

Nr. 08 06 H. Fernau Parameterized Algorithms for d-HITTING Set: the Weightes Case http://www.mathematik.uni-trier.de/tf/08_06.pdf Nr. 08 05 H. Fernau, D. Raible Exact Algorithms for Maximum Acyclic Subgraph on a Superclass of Cubic Graphs http://www.mathematik.uni-trier.de/tf/08_05.pdf Nr. 08 04 R. Tichatschke Auf den Schultern von Giganten: Zur Geschichte der Mathematischen Optimierung http://...

The interaction between isatin-β-thiosemicarbazone (IBT) and calf thymus DNA (CT-DNA) was investigated in physiological buffer (pH 7.4) using Neutral Red (NR) dye as a spectral probe by UV–Vis absorption and fluorescence spectroscopy, as well as viscosity measurements. The IBT is stabilized by intercalation in the DNA ( K [IBT –DNA] =1.03×105 M−1), and displaces the NR dye from the NR–DNA comple...

Higher plant nitrate reductases (NRs) carry an N-terminal domain whose sequence is not conserved in NRs from other organisms. A gene composed of a full-length tobacco NR cDNA with an internal deletion of 168 bp in the 5' end fused to the cauliflower mosaic virus 35S promoter and appropriate termination signals was constructed and designated as delta NR. An NR-deficient mutant of Nicotiana plumb...

Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we determine the time and dose-dependent effects of NR on blood NAD+ metabolism in humans. We report that human blood NAD+ can rise as much as 2.7-fold with a single oral dose of NR in a pilot study of one individual, and that oral NR elevates mouse hepatic NAD+ with distinct and superior pharmacokinetics to those of n...

The mechanism of nitrate reductase (NR) regulation under long-term anoxia in roots of whole plants and the putative role of nitrate in anoxia tolerance have been addressed. NR activity in tomato roots increased significantly after 24 h of anaerobiosis and increased further by 48 h, with a concomitant release of nitrite into the culture medium. Anoxia promoted NR activation through dissociation ...