نتایج جستجو برای: تمرینات trx

تعداد نتایج: 6523  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2001
H Nakamura L A Herzenberg J Bai S Araya N Kondo Y Nishinaka J Yodoi

Thioredoxin (Trx), a redox enzyme with a conserved active site (Cys-32-Gly-Pro-Cys-35), is induced and secreted into circulation in response to inflammation. Studies here demonstrate that elevating Trx levels in circulation either by i.v. injection of recombinant Trx or stimulating Trx release in Trx-transgenic mice dramatically blocks lipopolysaccharide (LPS)-stimulated neutrophil migration in...

Journal: :Current Biology 2017
Carolina Werner Ribeiro Fabien Baldacci-Cresp Olivier Pierre Marie Larousse Sofiane Benyamina Annie Lambert Julie Hopkins Claude Castella Julie Cazareth Geneviève Alloing Eric Boncompagni Jérémy Couturier Peter Mergaert Pascal Gamas Nicolas Rouhier Françoise Montrichard Pierre Frendo

Legumes associate with rhizobia to form nitrogen (N2)-fixing nodules, which is important for plant fitness [1, 2]. Medicago truncatula controls the terminal differentiation of Sinorhizobium meliloti into N2-fixing bacteroids by producing defensin-like nodule-specific cysteine-rich peptides (NCRs) [3, 4]. The redox state of NCRs influences some biological activities in free-living bacteria, but ...

2013
JiangWei Hu ZaiLiang Yang Jun Wang YongYong Tang Hao Liu Bin Zhang Hu Chen

A protective reagent for ARI should have the ability to repair injured tissue caused by radiation and prevent continuous damage from secondary risk factors. Trx-1 was explored as a candidate therapy for ARI, as it scavenges reactive oxygen species, regulates cell growth and differentiation, participates in immune reactions, and inhibits apoptosis by acting inside and/or outside cells. Trx-1 can...

Journal: :Nucleic Acids Research 2006
Ruiqing Yang David J. Weber France Carrier

Thioredoxin (TRX) is a key protein of the cellular redox metabolism, which expression is increased in several tumors especially gastric tumors. Even though ultraviolet (UV) and hypoxia specifically induce TRX, the mechanisms that lead to increased TRX levels are still ill defined. Here, we show that the heterogenous ribonucleoprotein A18 (hnRNP A18) RNA Binding Domain (RBD) and the arginine, gl...

Journal: :Life sciences 2010
Xiaoping Chen Wenxin Tang Shan Liu Longjiang Yu Zhengwang Chen

AIMS Thioredoxin-1 (Trx) is an important protein involved in the regulation of apoptosis and in enhancing drug resistance in cancer cells. Threonine100 (T100) of Trx was reported to be phosphorylated; however, the role of this phosphorylation in regulating activity remains unresolved. We explored whether and how the phosphorylation of Trx is involved in drug resistance in cancer cells. MAIN M...

ژورنال: طب توانبخشی 2019

مقدمه و اهداف کمردرد به عنوان یکی از شایع­ترین و پرهزینه ­ترین مشکلات طبی و علت اصلی غیبت از کار است. پژوهش حاضر با هدف بررسی تاثیر تمرینات ثبات مرکزی رایج و تمرینات تعلیقی ویژه بر درد و ناتوانی عملکردی افراد دارای کمردرد مزمن غیراختصاصی انجام شد. مواد و روش ­ها جامعه آماری تحقیق نیمه ­تجربی حاضر، بیماران مبتلا به کمردرد مزمن مراجعه­کننده به ک...

2014
Carolin C. Lechner Christian F.W. Becker

1.1 Materials ........................................................................................................................ 2 1.2 Instrumentation .............................................................................................................. 2 1.3 HPLC and mass spectrometry ........................................................................................ 3 1.4 C...

2015
Kento Nishida Hiroshi Watanabe Shigeru Ogaki Azusa Kodama Ryota Tanaka Tadashi Imafuku Yu Ishima Victor Tuan Giam Chuang Masao Toyoda Masumi Kondoh Qiong Wu Masafumi Fukagawa Masaki Otagiri Toru Maruyama

Rhabdomyolysis-associated acute kidney injury (AKI) is a serious life-threatening condition. As such, more effective strategies are needed for its prevention. Thioredoxin-1 (Trx), a redox-active and macrophage migration inhibitory factor (MIF) modulating protein, has a short retention time in the blood. We examined the renoprotective effect of long acting Trx that was genetically fused with hum...

2009
Goedele Roos Nicolas Foloppe Koen Van Laer Lode Wyns Lennart Nilsson Paul Geerlings Joris Messens

The dissociation mechanism of the thioredoxin (Trx) mixed disulfide complexes is unknown and has been debated for more than twenty years. Specifically, opposing arguments for the activation of the nucleophilic cysteine as a thiolate during the dissociation of the complex have been put forward. As a key model, the complex between Trx and its endogenous substrate, arsenate reductase (ArsC), was u...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Eric Gelhaye Nicolas Rouhier Joelle Gérard Yves Jolivet José Gualberto Nicolas Navrot Per-Ingvard Ohlsson Gunnar Wingsle Masakazu Hirasawa David B Knaff Hongmei Wang Pierre Dizengremel Yves Meyer Jean-Pierre Jacquot

The plant mitochondrial thioredoxin (Trx) system has been described as containing an NADPH-dependent Trx reductase and Trx o. In addition to the mitochondrial isoform, Trx o, plants are known to contain several chloroplastic Trx isoforms and the cytosolic Trx h isoforms. We report here the presence in plant mitochondria of a Trx isoform (PtTrxh2) belonging to the Trx h group. Western blot analy...

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