PURPOSE To answer the question whether the TSI (tissue strain imaging) sonoelastography technique can contribute to the diagnosis of chronic renal allograft damage. MATERIAL AND METHODS A prospective study of 112 patients between June 2010 and April 2011 was conducted to compare elastography data with biopsy results and laboratory parameters in order to determine whether any correlations exis...

Feature selection on high-dimensional networks plays an important role in understanding of biological mechanisms and disease pathologies. It has a broad range of applications. Recently, a Bayesian nonparametric mixture model (Zhao, Kang, and Yu 2014) has been successfully applied for selecting gene and gene sub-networks. We extend this method to a unified approach for feature selection on gener...

CXCR3, a chemokine receptor mainly expressed by T cells, is involved in animal transplant models and in human allograft rejection. CXCR3 expression was localized in formalin-fixed, paraffin-embedded renal allograft biopsies without signs of rejection (C4d-negative, Banff 0, n = 16), with C4d deposits as a sign of humoral rejection (C4d-positive, Banff 0, n = 8), with cellular rejection (C4d-neg...

From small beginnings in 1991, the Banff working classification of renal allograft pathology has grown to be a major force for setting standards in renal transplant pathology, and is widely used in international clinical trials of new antirejection agents. The meeting, classification, and consensus process have unique history, and look poised to continue for another several decades as the embod...

Refugia can affect predator-prey dynamics via movements between refuge and non-refuge areas. We examine the influence of a refuge on population dynamics in a large mammal predator-prey system. Wolves (Canis lupus) have recolonized much of their former range in North America, and as a result, ungulate prey have exploited refugia to reduce predation risk with unknown impacts on wolf-prey dynamics...