Integrated circuits sensitive to both total ionizing dose (TID) and displacement damage (DD) effects can exhibit degradation profiles resulting from a combination of mechanisms induced by effects. This work presents circuit simulations based on experimental data explain combined TID DD bipolar IC current source. First, the effect each internal transistor circuit's response is evaluated applying...

We present a statistical study of Traveling Ionospheric Disturbances (TIDs) as observed by the EISCAT Svalbard Radar (ESR) during the continuous IPY-run (March 2007–February 2008) with field-aligned measurements. We have developed a semi-automatic routine for searching and extracting Atmospheric Gravity Wave (AGW) activity. The collected data shows that AGW-TID signatures are common in the high...

OBJECTIVE Famotidine given at a dose of 80 mg/day is effective in preventing NSAID-induced gastropathy. The aim of this proof of concept study was to compare twice a day (BID) vs 3-times a day (TID) administration of this total dose of famotidine on intragastric pH in healthy volunteers. RESEARCH DESIGN AND METHODS Two analyses were undertaken: (1) a 13 subject controlled cross-over 24-h intr...

Five experiments utilizing 3,628 pigs were conducted to determine the true ileal digestible (TID) Lys requirement for 11- to 27-kg pigs fed corn-soybean meal diets. In Exp. 1, 216 barrows (initial BW = 11.5 kg) were used, with dietary TID Lys levels from 1.05 to 1.40% TID Lys (0.07% increments). All diets were isocaloric (3.42 Mcal of ME) and contained the same inclusion of soybean meal (33.1%)...

This study explored to which extent the development of German professional football players is based on early talent identification (TID) and long-term nurture in talent promotion (TP) programmes or on their emergence in the course of repeated procedures of player selection and de-selection in these programmes through childhood and youth. The annual turnover of squad members in national junior ...

Chronic kidney disease (CKD) in dogs is the final common pathway resulting from persistent renal injury and is characterized by progressive tubulointerstitial damage (TID). Pathogenesis of CKD is divided into an initial inflammatory phase with a predominantly mononuclear infiltrate followed by a fibrotic phase with increased numbers of fibroblasts and extracellular matrix deposition that causes...

BACKGROUND The main aim of this study was to compare the safety and efficacy of IR MPH administered three times daily to those of once daily OROS-MPH. METHODS Subjects were outpatient adults satisfying full diagnostic criteria for DSM-IV ADHD between 19 and 60 years of age. Data from two independently conducted 6-week placebo controlled, randomized clinical trials of IR-MPH (tid) and of OROS-...

The role of Th17 cells in type I diabetes (TID) remains largely unknown. Glutamic acid decarboxylase (GAD) sequence 206-220 (designated GAD2) represents a late-stage epitope, but GAD2-specific T cell receptor transgenic T cells producing interferon gamma (IFNgamma) protect against passive TID. Because IFNgamma is known to inhibit Th17 cells, effective presentation of GAD2 peptide under noninfla...

BACKGROUND Although poststress myocardial stunning is regarded as a marker for severe coronary artery disease (CAD), no study has yet compared the diagnostic value of poststress stunning with transient ischemic dilation (TID) of the left ventricle (LV) for detecting multivessel CAD. METHODS AND RESULTS A total of 271 patients with suspected or known CAD underwent adenosine triphosphate (ATP) ...

BACKGROUND The noninferiority of pH-dependent release mesalamine (Asacol) once daily (QD) to 3 times daily (TID) administration was investigated. METHODS This was a phase 3, multicenter, randomized, double-blind, parallel-group, active-control study, with dynamic and stochastic allocation using central registration. Patients with ulcerative colitis in remission (a bloody stool score of 0, and...