UNLABELLED We aimed at establishing the optimal scan time for nuclear myocardial perfusion imaging (MPI) on an ultrafast cardiac gamma-camera using a novel cadmium-zinc-telluride (CZT) solid-state detector technology. METHODS Twenty patients (17 male; BMI range, 21.7-35.5 kg/m(2)) underwent 1-d (99m)Tc-tetrofosmin adenosine stress and rest MPI protocols, each with a 15-min acquisition on a st...

This pathway describes the development of soft gamma-ray/hard x-ray detector arrays at NASA’s Goddard Space Flight Center (GSFC, or Goddard), through a collaboration between the gamma-ray spectroscopy group and the detector branch. The Cadmium Zinc Telluride (CdZnTe, or CZT) detectors which resulted from this decade-long development were first flown on the wildly successful SWIFT mission in 200...

Several astrophysics and nuclear physics applications require the detection of photons in the energy range of keV up to several MeV with good position and energy resolution. For certain applications Cadmium Zinc Telluride (CZT) detectors might be the detector option of choice. Up to now, CZT detectors have mainly been used in the energy range between a few keV and ∼1 MeV. They operate at room t...

McMaster University, Canada While mammography is the gold standard for breast cancer screening, it suffers from poor sensitivity in women with dense breast tissue. Both breast MRI and molecular breast imaging (MBI) have been used as secondary imaging techniques. However, breast MRI suffers from low specificity and low sensitivity in MBI. A CZT based detector system has been developed with the g...

CdZnTe (CZT) has made a significant impact as a material for room-temperature nuclear-radiation detectors due to its potential impact in applications related to nonproliferation, homeland security, medical imaging, and gamma-ray telescopes. In all such applications, common metals, such as gold, platinum and indium, have been used as electrodes for fabricating the detectors. Because of the large...

BACKGROUND Correction of motion has become feasible on cadmium-zinc-telluride (CZT)-based SPECT cameras during myocardial perfusion imaging (MPI). Our aim was to quantify the motion and to determine the value of automatic correction using commercially available software. METHODS AND RESULTS We retrospectively included 83 consecutive patients who underwent stress-rest MPI CZT-SPECT and invasiv...

We describe the detector development for a balloon-borne wide-field hard X-ray (20 – 600 keV) telescope, ProtoEXIST. ProtoEXIST is a pathfinder for both technology and science of the proposed implementation of the Black Hole Finder Probe, Energetic X-ray Imaging Survey telescope (EXIST). The principal technology challenge is the development of large area, close-tiled modules of imaging CZT dete...

We describe initial results of our program to develop and test Cd-Zn-Te (CZT) detectors with a pixellated array readout. Our primary interest is in the development of relatively thick CZT detectors for use in astrophysical coded aperture telescopes with response extending over the energy range ∼ 10 − 600 keV. The coded aperture imaging configuration requires only relatively large area pixels (1...

BACKGROUND The performance of a prototype novel digital single-photon emission computed tomography (SPECT) camera with multiple pixelated CZT detectors and high sensitivity collimators (Digital SPECT; Valiance X12 prototype, Molecular Dynamics) was evaluated in various clinical settings. Images obtained in the prototype system were compared to images from an analog camera fitted with high-resol...

Nuclear detectors for x-ray and gamma-ray spectroscopy imaging are a vital tool in many homeland security, medical imaging, astrophysics other applications. Most of these applications require room-temperature operation due to the operational constraints imposed by cryogenic cooling system. CdZnTe (CZT) has been main material with desired detection properties, CZT crystals have used commercially...