various plant organ segments including segments from roots (root tip, and root collar), stems, leaves, and also seeds of several hyoscyamus species (i.e. h. pusillus, h. arachnoideus, annual and biennial h. niger from two distinct geographical regions) were cultured on ms media with various growth regulator combinations, to assess the ability of flower production. statistical assessments showed...

background: regarding the prevalence of epilepsy in human society and with respect to inefficiency of the usual treatments, finding new strategies and methods for the medical treatment of epileptic patients are essential. henbane seed has been used in iranian traditional medicine as an anti-convulsion herb. with this regard the present study was carried out to consider the anti-convulsive effec...

This study was aimed to determine the effects of different concentrations L-phenylalanine (0.25, 0.50 and 1.00 mM L-Phe) applied adventitious root cultures for culture durations on growth production tropane alkaloids phenolics in Hyoscyamus niger. For this purpose, roots obtained from petiole explants vitro seedlings were used as plant materials. After cultured liquid Murashige Skoog (MS) mediu...

black henbane (bh) or hyoscyamus niger, has been used as a medicine since last centuries and has been described in all traditional medicines. it applies as a herbal medicine, but may induce intoxication accidentally or intentionally. all part of bh including leaves, seeds and roots contain some alkaloids such as hyoscyamine, atropine, tropane and scopolamine. bh has pharmacological effects like...

Hyoscyamine is epoxidized to scopolamine via 6beta-hydroxyhyoscyamine in several solanaceous plants. 6,7-Dehydrohyoscyamine has been proposed to be an intermediate in the conversion of 6beta-hydroxyhyoscyamine to scopolamine on the basis of the observation that this unsaturated alkaloid is converted to scopolamine when fed to a Datura scion. To determine whether a dehydration step is involved i...

Henbane, Hyoscyamus niger, is a hallucinogenic plant, widely spread and easy accessible, which contains anticholinergic substances. Ingestion, intentional or accidental, can provoke serious worsening of psychophysical state and can cause even death. Intoxication resembles the one with atropine. Symptoms like mydriasis, tachycardia, arrhythmia, agitation, convulsion and coma can appear. Diagnosi...