In the title compound, C(19)H(13)IN(2)O(2), the isoquinoline ring makes dihedral angles of 55.92 (3)° and 76.11 (3)° with the benzene and succinimide rings, respectively. The dihedral angle between the benzene and succinimide rings is 70.37 (3)°. In the crystal structure, the iodo atom deviates from the isoquinoline plane by 0.163 (1) Å. The crystal studied was found to be a racemic twin with a...

Isoquinoline 1-oxidoreductase (IOR) from Brevundimonas diminuta is a mononuclear molybdoenzyme of the xanthine-dehydrogenase family of proteins and catalyzes the conversion of isoquinoline to isoquinoline-1-one. Its primary sequence and behaviour, specifically in its substrate specificity and lipophilicity, differ from other members of the family. A crystal structure of the enzyme is expected t...

The mol-ecular structure of the title compound, C(26)H(18)N(4)O(6)S·C(2)H(6)OS, shows an E conformation of the hydrazone double bond. The presence of a methyl-ene group between the benzo[de]isoquinoline and benzene-sulfonyl moieties allows the 4-nitro-phenyl ring and the benzo[de]isoquinoline system to be parallel with respect to each other, so that the mol-ecule adopts a U-shaped spatial confo...

ligands derived from 8-quinoline, 6-quinoline, 1 -isoquinoline, and 5-isoquinoline were synthesized. these compounds have been used as ligands for complexation of transition metals, such as copper(ii) and nickel(ii). according to the spectrosocopic data, copper(ii) cation forms (i: 1) and (i:2) complexes with 2-(8-quinoly1)-l,l,3,3- tetramethylguanidine and 2- (i '-isoquinoly1)- 1,1,3,3-te...

The incorporation rates of labelled tyrosine, D O P A , tyramine, and dopamine have been inves­ tigated during the in vivo formation of the protoberberine alkaloid, jatrorrhizine, in callus cul­ tures o f Berberis canadensis. W hile tyrosine was equally well incorporated into both the isoquinoline (54% ) and benzyl (46% ) portions o f the alkaloid. D O PA was almost exclusively (91%) transforme...

Ligands derived from 8-quinoline, 6-quinoline, 1 -isoquinoline, and 5-isoquinoline were synthesized. These compounds have been used as ligands for complexation of transition metals, such as copper(II) and nickel(II). According to the spectrosocopic data, copper(II) cation forms (I: 1) and (I:2) complexes with 2-(8-quinoly1)-l,l,3,3- tetramethylguanidine and 2- (I '-isoquinoly1)- 1,1,3,3-tetr...

In the title coordination compound, [Cu(NCS)(C(9)H(7)N)(C(18)H(15)P)](n), the Cu(I) atom is tetra-hedrally coordinated by one N atom from an isoquinoline ligand, one P atom from a triphenyl-phospane ligand, and one N and one S atom from two thio-cyanate anions. The thio-cyanide anions bridge the Cu(I) atoms into a chain along [100]. π-π inter-actions between the pyridine and benzene rings of th...

The crystal structures of the Werner clathrates Ni(NCS)2(isoquinoline)4 (H) with para-xylene (px), meta-xylene (mx) and ortho-xylene (ox) have been elucidated. The kinetics of thermal decomposition of the three inclusion compounds were performed using the isothermal technique of Flynn and Wall. Selectivity of H for the xylene isomers was determined for both the liquid and vapour phase binary mi...

thiophosgene and 1-chloroethyl chlorothionoformate react readily with tertiary amines, and give the dialkylamine hydrochloride after hydrolysis of the initial product with water. benzyl and allyl groups are cleaved in preference to methyl and other alkyl groups. the rection with the isoquinoline alkaloid narcotine occurs particularly easily.