نتایج جستجو برای: اپیگالوکاتچین گالات egcg
تعداد نتایج: 1826 فیلتر نتایج به سال:
چای سفید، حداقل فرآوری شده، از غنجه و 1 تا 2 برگ خیلی جوان بعد از غنچه گیاه چای، که تحت عمل اکسایش قرار نگرفته تولید می شود و منسوب به بالاترین محتوای ترکیبات فنلی است. کاتچین های چای، آنتی اکسیدان های قوی، ترکیبات فعال زیستی و دارای فواید سلامت بخش هستند. کافئین اثر سینرژیست بر اثرات مفیدکاتچین ها دارد. در این پژوهش اثر دما و زمان دم آوری بر روی میزان کل کاتچین ها وکافئین چای سفید به روش hplcم...
در این پژوهش آثار پروپیل گالات که از فعالیت اکسیداز انتهایی پلاستید دخیل در تنفس کلروپلاستی جلوگیری می¬کند، بر کارایی فتوسیستم II در جلبک سبز تک سلولی Dunaliella salina با استفاده از اندازه¬گیری کینتیک فلوئورسنس کلروفیل a مطالعه شده است. تیمار کشتهای جلبکی با غلظتهای 1/0، 5/0، 1، 2 و 4 میلی¬مولار پروپیل گالات نشان داد که کارایی فتوسیستم II در حضور غلظتهای تا 1 میلی¬مولار افزایش یافته...
(-)-Epigallocatechin gallate (EGCG) and (-)-epigallocatechin (EGC) are the major polyphenolic constituents in green tea. In this study, we characterized the enzymology of cytosolic catechol-O-methyltransferase (COMT)-catalyzed methylation of EGCG and EGC in humans, mice, and rats. At 1 microM, EGCG was readily methylated by liver cytosolic COMT to 4"-O-methyl-EGCG and then to 4',4"-di-O-methyl-...
Due to the anti-diabetic and antioxidant activity of green tea epigallocatechin-gallate (EGCG), this research study was conducted to evaluate, for the first time, the efficacy of chronic treatment of EGCG on alleviation of hyperalgesia in streptozotocin-diabetic (STZ-diabetic) rats. Male Wistar rats were divided into control, diabetic, EGCG-treated-control and diabetic and sodium salicylate (SS...
(-)-Epigallocatechin-3-gallate (EGCG), the major bioactive constituent in green tea, has been reported to effectively inhibit the formation and development of tumors. To maximize the effectiveness of EGCG, we attached it to nanogold particles (EGCG-pNG) in various ratios to examine in vitro cytotoxicity and in vivo anti-cancer activity. EGCG-pNG showed improved anti-cancer efficacy in B16F10 mu...
This study evaluated epigallocatechin-3-gallate (EGCG) and epigallocatechin-3-O-(3-O-methyl)-gallate (EGCG-3Me) modified etch-and-rinse adhesives (Single Bond 2, SB 2) for their antibacterial effect and bonding stability to dentin. EGCG-3Me was isolated and purified with column chromatography and preparative high performance liquid chromatography. EGCG and EGCG-3Me were incorporated separately ...
Epigallocatechin gallate (EGCG), the main polyphenolic substance in tea, exhibits well-known biological benefits. In order to improve fat solubility and bioavailability, a novel path for lipase enzymatic transesterification synthesis of acylated EGCG derivatives an ionic liquid solvent was established. The optimal reaction parameters were determined maximum conversion achieved at 98.65%. [Bmim]...
Epigallocatechin gallate (EGCG), one of the major catechins found in green tea, was suggested to play a role as a chemopreventive agent in various human cancer models. In this study, we reported that EGCG has a profound antitumor effect on human tongue carcinoma cells by directly regulating glycolysis. EGCG dose-dependently inhibited anchorage-independent growth and short-term EGCG exposure sub...
Polyphenol (-)-epigallocatechin gallate (EGCG), the most abundant catechin of green tea, appears to attenuate myocardial ischemia/reperfusion injury. We investigated the involvement of ATP-sensitive potassium (K(ATP)) channels in EGCG-induced cardioprotection. Isolated rat hearts were subjected to 30 min of regional ischemia and 2 hr of reperfusion. EGCG was perfused for 40 min, from 10 min bef...
(-)-Epigallocatechin-3-gallate (EGCG) is the most extensive studied tea polyphenol for its anti-cancer function. In this study, we report a novel mechanism of action for EGCG-mediated cell death by identifying the critical role of lysosomal membrane permeabilization (LMP). First, EGCG-induced cell death in human cancer cells (both HepG2 and HeLa) was found to be caspase-independent and accompan...
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