Astragalus L., is one of the largest genuses of flowering plants in the Leguminosae family. Roots of A. membranaceus Bge. var. mongholicus (Bge.) Hsiao, A. membranaceus (Fisch.) Bge. and its processed products are listed in the China Pharmacopeia for "qi deficiency" syndrome treatment. However, more and more researches on other species of Astragalus have been conducted recently. We summarize th...

Background and objectives: Traditional medicine is an important approach to achieve new therapeutic strategies in basic and clinical pharmacology. Allium hirtifolium Boiss. and Astragalus hamosus L. have been mentioned in Iranian Traditional Medicine references for a kind of dementia with features and symptoms similar to those of Alzheimer's disease (AD). In the present study, the neuroprotecti...

Sulfate and selenate uptake were investigated in both selenium (Se) hyperaccumulators (Astragalus racemosus and Astragalus bisulcatus) and closely related nonaccumulator species (Astragalus glycyphyllos and Astragalus drummondii). Sulfur (S) starvation increased Se accumulation, whereas increased selenate supply increased sulfate accumulation in both root and shoot tissues. cDNAs for homologs o...

BACKGROUND Astragalus memebranaceus is a traditional Chinese herbal medicine used in treatment of common cold, diarrhea, fatigue, anorexia and cardiac diseases. Recently, there are growing evidences that Astragalus extract may be a potential anti-tumorigenic agent. Some research showed that the total saponins obtained from Astragalus membranaceus possess significant antitumorigenic activity. Ga...

Astragalus membranaceus is commonly used in traditional Chinese medicine for strengthening the host defense system. Astragalus membranaceus-polysaccharides is an effective component with various important bioactivities, such as immunomodulation, antioxidant, anti-diabetes, anti-inflammation and neuroprotection. In the present study, we determine the effects of Astragalus membranaceus-polysaccha...

Astragalus polysaccharide is an important bioactive component of Astragalus membranaceus, an herb used in traditional Chinese medicine for treating inflammatory bowel disease. The NOD-like receptor protein 3 inflammasome plays an important role in the pathogenesis of inflammatory bowel disease. However, little is known about the role of NOD-like receptor protein 3 inflammasome in Astragalus pol...