Imaging mass spectrometry (IMS) has recently established itself in the field of "spatial metabolomics." Merging the sensitivity and fast screening of high-throughput mass spectrometry with spatial and temporal chemical information, IMS visualizes the production, location, and distribution of metabolites in intact biological models. Since metabolite profiling and morphological features are combi...

Background Obstructive sleep apnoea (OSA) is related to type 2 diabetes (T2DM), and it may be associated with reduced inspiratory muscle strength (IMS). The aim of this study was to investigate the IMS in patients with T2DM, with or without OSA. Methods Patients with T2DM with OSA (n = 33) and without OSA (n = 28) were included. The maximum IMS was tested using the POWERbreathe KH2 device. Re...

The main goal of this study was to apply magnetic bead surface functionalization in the form immunomagnetic separation (IMS) combined with real-time polymerase chain reaction (qPCR) (IMS-qPCR) detect Human mastadenovirus species C (HAdV-C) and F (HAdV-F) water samples. technique efficiency compared a nonfunctionalized method (ultracentrifugation) followed by laboratory detection. Tests were car...

various techniques and culture media were developed for rapid identification of salmonella serovars. however, there are still problems with their sensitivity and specificity. in an attempt to reduce the time spent to obtain a result and to minimize the problems associated with rapid detection systems such as interference from food ingredients debris, micro flora in feces, and lack of sensitivit...

This article presents a methodology for developing learning objects for web-based courses using the IMS Learning Design (IMS LD) specification. We first investigated the IMS LD specification, determining how to use it with online courses and the student delivery model, and then applied this to a Unit of Learning (UOL) for online computer science courses. We developed an editor and runtime envir...

This work proposes a novel metric, Maximally Amortized Cost (MAC), for cost evaluations of error correction of predictive Chinese input methods (IMs). With a series of real-time simulation, user correction behaviors are analyzed by estimating generalized backward compatibility of adaptive Chinese IMs. Comparisons between three IMs by using MAC with different context lengths report empirical fac...

IP Multimedia Subsystem (IMS) as the core of Next Generation Network (NGN), its security is vital important. However, IMS is a network with openarchitecture based on IP, which brings a lot of security issues. There has already some research results about IMS security, but systematic and model-based research results are lacked. Based on TVRA method, this paper establishes a comprehensive vulnera...

Macrophages play a key role in the innate immune system. Macrophages are thought to originate from hematopoietic precursors or the yolk sac. Here, we describe the in vitro establishment of self-renewable GM-CSF-dependent immature macrophages (GM-IMs) from murine bone marrow (BM). GM-IMs grow continuously in vitro in conditioned medium containing GM-CSF. The immunophenotype of GM-IMs is F4/80(hi...