conclusions in the case of existence gaussian noise, the results confirm that denoising is not effective on the measurement of t2* value. in the case of image distortion by rician noise, a predictor model is proposed to estimate the original t2* value. the predictor model is used to estimate the t2* value of new patients. the predicted t2* values were in good agreement with the corresponding or...

background: iron-mediated cardiomyopathy is the main complication of thalassemia major (tm) patients. therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. the aim of this study was to evaluate the efficacy of tissue doppler imaging (tdi) to study cardiac iron overload in patients with tm using t2* magnetic resonance (mr) as the gold-standard...