Here we briefly review our information theoretic approach to revealing community structure in weighted and directed networks [1] and present a new fast stochastic and recursive search algorithm to minimize the map equation — the objective function of our method. We have developed this algorithm to be able to accurately partition the large number of bootstrap networks [2]. The search algorithm c...

The double exponential model t t M T Be Ae vl μ μ − − + = was fitted to log10(vl) data from day 0 to day 28 post ART. When vl was undetectable it was replaced with the limit of detection (80 copies per ml), indicated by the dashed line in Figure S1 and S2. Fits were performed by nonlinear least squares regression, confidence intervals were calculated by bootstrapping the cases and trimming the ...

There are several downstream analysis goals for which RNA-seq is well suited. Main categories of these are described briefly below with reference to supporting materials. Refer to S2 Table for specific tools relevant to many of these areas. For each application, a basic data recommendation is provided. It is important to remember that these are simply examples. In addition to the varying demand...

Comment on reversibility We and others have observed differences in the reversibility measured by the QPatch instrument and by manual patch clamp: washout of lipophilic compounds is delayed in the QPatch. The probable reason for this is the presence of unrecorded cells within the chip. One major difference as compared to manual patch clamp is that QPatch does not allow continuous flow of extrac...