background: intracytoplasmic sperm injection (icsi) is an advanced technique employed in assisted reproductive clinics for treatment of infertile couples. the reproductive endocrinologists try their level best to identify factors that enhance success rate after icsi. objective: to compare estradiol progesterone ratio on ovulation induction day amongst pregnancy outcome groups following icsi. ma...

BACKGROUND Women with recurrent ectopic pregnancy (EP) represent a unique cohort of patients in whom diagnostic expertise is paramount. We determined whether recurrent EP is associated with significant differences in patient demographics, clinical presentation, risk factors and surgical findings when compared with primary EP. METHODS A retrospective case-control study of all EPs diagnosed fro...

ectopic pregnancy (ep) and miscarriage are important differential diagnosis of first trimester vaginal bleeding. in first trimester, serum progesterone value can be 5-20 ng/ml in ep and miscarriage. since delay in diagnosis of ep could have high mortality and morbidity, the aim of this study was comparison of serum progesterone value in ep and miscarriage in order to differentiate these conditi...

BACKGROUND StAR-related lipid transfer domain containing 7 (StarD7) is a member of the START-domain protein family whose function still remains unclear. Our data from an explorative microarray assay performed with mRNAs from StarD7 siRNA-transfected JEG-3 cells indicated that ABCG2 (ATP-binding cassette sub-family G member 2) was one of the most abundantly downregulated mRNAs. METHODOLOGY/PRI...

BACKGROUND Krüppel-like factor-6 (KLF6) is a widely expressed member of the Sp1/KLF family of transcriptional regulators involved in differentiation, cell cycle control and proliferation in several cell systems. Even though the highest expression level of KLF6 has been detected in human and mice placenta, its function in trophoblast physiology is still unknown. METHODOLOGY/PRINCIPAL FINDINGS ...

Aim. To assess the impact of iodine status in early pregnancy on thyroid function. Methods. Women >18 years old seen at their first prenatal consult before 12 weeks of amenorrhea and without personal thyroid history were proposed thyroid screening and were eligible if they had strictly normal thyroid tests (fT4 > 10th percentile, TSH < 2.5 mUI/L, negative anti-TPO antibodies). Evaluation includ...

background: there has been an increase in number of obese infertile females booked for advanced infertility treatment procedures like in vitro fertilization (ivf) and intra cytoplasmic sperm injection (icsi). the knowledge of impact of body mass index (bmi) on reproductive outcome can help to counsel these patients. objective: to compare reproductive outcome in females of different bmi after ic...