in order to study the effects of various levels of protein in diet based on total and digestible amino acids on performance and carcass traits of broilers, an experiment was conducted as a completely randomized design with 288 broiler chicks from cobb 500 strain in 6 treatments, each treatment consist of 3 replicates with 16 chicks per replicate. treatments were the diets as follow: 1) diet for...

A new Ir(III)-NHC catalyst is reported that shows remarkable activity in the N-alkylation of unprotected amino acids. The catalytic system gives excellent selectivity toward monoalkylated α-amino acids and a high degree retention stereochemistry. wide range nonnatural have been prepared. These compounds represent an array building blocks could be used for direct synthesis peptidomimetics. amino...

The utility of pseudoephenamine as a chiral auxiliary for the alkylative construction of quaternary α-methyl α-amino acids is demonstrated. The method is notable for the high diastereoselectivities of the alkylation reactions, for its versatility with respect to electrophilic substrate partners, and for its mild hydrolysis conditions, which provide α-amino acids without salt contaminants. Alter...

A one-pot approach to β-branched β-trifluoromethyl α-amino acids, grounded on the reduction – ring opening of Erlenmeyer–Plöchl azlactones, and complementary conventional catalytic asymmetric hydrogenation, is presented.

Peptidomimetics based on hydrazino derivatives of α-amino acids represent an important class of peptidic foldamers with promising biological activities, like protease inhibition and antimicrobial activity. However, the lack of straightforward method for the synthesis of optically pure hydrazino acids and efficient incorporation of hydrazino building blocks into peptide sequence hamper wider exp...