Around 10% of males with idiopathic azoospermia or oligozoospermia, which are important causes of male infertility, have partial deletions on the long arm of the Y chromosome. To develop a rapid and accurate detection system for screening major Y deletions found in infertile men, we developed a multiplex PCR system that can simultaneously amplify five loci on the Y chromosome, SRY, AMELY, DBY, ...

Abnormal Y chromosome includes Yq– of various extents (excluding normal Yq variation), Yp–, r(Y), and isochromosomes or isodicentric chromosomes, written variously as i(Yp), idic(Yp), i(Yq), and idic(Yq) [1]. The least rare of these rare conditions is the Y isochromosome, or isodicentric chromosome, usually seen as 46,X,i(Y)(p10) or 46,X,i(Y) (q11), in which the essential imbalance is a double ...

We show how to compute the pre-images of multiplication by 3 in group points an elliptic curve E over a field k characteristic different from 2 and such that E[3](k)=E[3]. Q=(xQ,yQ)∈[3]E(k) if only yQ−d−m(xQ−c) is cube for every 3-torsion point (c,d)∈E[3], where m slope tangent at (c,d). reduce our problem computation most independent cubic roots plus few polynomial operations.

phenotypically normal females with secondary amenorrhea and translocation between Xq and Yq. To the best of our knowledge, the detection of Xq;Yq translocation at prenatal diagnosis has not been reported. Herein, we report the prenatal diagnosis of a de novo unbal­ anced Xq;Yq translocation for the first time and discuss issues in genetic counseling to be given to patients with this particular ...

Deletions on the mouse Y-chromosome long arm (MSYq) lead to teratozoospermia and in severe cases to infertility. We find that the downstream transcriptional changes in the testis resulting from the loss of MSYq-encoded transcripts involve upregulation of multiple X- and Y-linked spermatid-expressed genes, but not related autosomal genes. Therefore, this indicates that in normal males, there is ...

This study was carried out to analyze the vertical transmission of Yq AZFc microdeletions from father to son in infertile Han Chinese families to investigate genetic factors and family background affecting fertility status. The peripheral blood of infertile males in 19 Han families was extracted and screened with modified multiplex polymerase chain reaction (PCR). Family trees were drawn accord...

A fetus was prenatally diagnosed as having a Y(nfqs) chromosome which was inherited from the father. With the QFQ technique, the Yqh was observed to be nonfluorescent and contained cytological satellites which were attached to the terminal long arm. The satellites were positively stained by the Ag-NOR technique suggesting that the NORs were active. A battery of DNA probes was used to characteri...