Background: Diet may be involved in the strong dose-response relation of -glutamyltransferase (GGT) concentration with incident

Motor abundance allows individuals to perform any task reliably while being variable in movement's particulars. The study investigated age-related differences in this feature when young adults (YA) and older adults (OA) performed challenging tasks, namely treadmill walking alone and while performing a cognitive task. A goal function for treadmill walking was first defined, i.e., maintain consta...

1 Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN. 2 Division of Epidemiology and Forensic Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan. 3 Department of Nutrition, University of Oslo, Oslo, Norway. 4 Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota, Minneapolis, MN. 5 Department of Pre...

OBJECTIVE To determine whether duration and degree of weight gain are differentially associated with diabetes risk in younger versus middle-aged black and white adults. RESEARCH DESIGN AND METHODS We combined data from three cohort studies: Atherosclerosis Risk in Communities (ARIC), Coronary Artery Risk Development in Young Adults (CARDIA), and the Framingham Heart Study. A total of 17,404 p...

BACKGROUND The association of murine asthma with adiposity may be mediated by adiponectin, an anti-inflammatory adipokine with reduced serum concentrations in obese subjects. A study was undertaken to examine whether the serum adiponectin concentration is associated with human asthma and whether it explains the association between adiposity and asthma, particularly in women and in premenopausal...

Yield pressure at the cardia was measured before and after fundoplication in 10 patients; five had a Nissen fundoplication and five a Belsey mark IV procedure. Surgery was considered successful if oesophagitis healed or if 24 hour pH monitoring returned to normal. There was a marked rise in yield pressure in all eight patients with a successful operation. Yield pressure remained low in two pati...

Inflammatory processes are implicated in a number of diseases for which there are known socioeconomic status (SES) disparities, including heart disease and diabetes. Growing evidence also suggests SES gradients in levels of peripheral blood markers of inflammation. However, we know little about potential gender and racial/ethnic differences in associations between SES and inflammation, despite ...

BACKGROUND Neighborhood transportation infrastructure and public recreational facilities are theorized to improve the activity, weight, and cardiometabolic profiles of individuals living in close proximity to these resources. However, owing to data limitations, there has not been adequate study of the influence of timing and placement of new infrastructure on health over time. METHODS This pr...

Greater levels of socioeconomic position (SEP) are generally associated with better health. However results from previous studies vary across race/ethnicity and health outcomes. Further, the majority of previous studies do not account for the effects of life course SEP on health nor the effects of racial discrimination, which could moderate the effects of SEP on health. Using data from the Coro...

OBJECTIVE To examine the prospective association of depressive symptoms with circulating C-reactive protein (CRP) and to determine the direction of that association. METHODS Using data from 2,544 healthy participants in the Coronary Artery Risk Development in Young Adults study (ages, 33-45 years; 55% female; 42% black), we examined the prospective association of depressive symptoms, as measu...