نتایج جستجو برای: yolk lycopene

تعداد نتایج: 11399  

Journal: :Basic & clinical pharmacology & toxicology 2007
Ana Lucia Anjos Ferreira Robert Mitchell Russell Noeme Rocha Marcelo Sady Placido Ladeira Daisy Maria Favero Salvadori Maria Carolina Munhoz Oliveira Nascimento Mirna Matsui Flavio Augusto Carvalho Guangwen Tang Luiz Shiguero Matsubara Beatriz Bojikian Matsubara

Doxorubicin is an excellent chemotherapeutic agent utilized for several types of cancer but the irreversible doxorubicin-induced cardiac damage is the major limitation for its use. Oxidative stress seems to be associated with some phase of the toxicity mechanism process. To determine if lycopene protects against doxorubicin-induced cardiotoxicity, male Wistar rats were randomly assigned either ...

Azadeh Abdi Gholamreza Karimi, Mohammad Ramezani

       The protective effect of tomato extract and lycopene on acute doxorubicin-induced myocardial toxicity was evaluated in mice. Doxorubicin toxicity, induced by a single intraperitoneal injection (15 mg/kg), was revealed by elevated serum CPKMB and histopathological observations. Tomato extract (1.2 and 2.4 g/kg, i.p.) and lycopene (1.7 and 3.5 mg/kg, i.p.), prevented the rise in serum CPKM...

Journal: :The British journal of nutrition 2006
Kati Fröhlich Karin Kaufmann Roland Bitsch Volker Böhm

Tomatoes are an important part of the diet. Lycopene, the predominant carotenoid in tomatoes, is hypothesised to mainly mediate the health benefits of tomato products. Anticancer activity of tomato products and lycopene has been suggested by numerous studies. The aim of the present study was to investigate the effect of ingestion of three different tomato-based foodstuffs on plasma contents of ...

Journal: :iranian journal of pharmaceutical research 0
mr safari

the intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. to clarify the possible role of lipophilic antioxidants in prevention of atherosclerosis, we investigated the effects of lycopene on the susceptibility of low-density lipoprotein (ldl) to oxidative modification. in this study, “lycopene” was added to plasma and incubated...

Journal: :The American journal of clinical nutrition 2015
Jung Eun Kim Susannah L Gordon Mario G Ferruzzi Wayne W Campbell

BACKGROUND Dietary lipids are one of the most effective stimulators of carotenoid absorption, but very limited data exist on the impact of endogenous food sources of lipids to enhance carotenoid absorption. The co-consumption of whole egg with carotenoid-rich foods may increase overall carotenoid absorption via lipid-rich egg yolk. OBJECTIVE We designed this study to assess the effects of egg...

Journal: :The American journal of clinical nutrition 2011
Alastair B Ross Le Thuy Vuong Jon Ruckle Hans Arno Synal Tim Schulze-König Karin Wertz Robert Rümbeli Rosa G Liberman Paul L Skipper Steven R Tannenbaum Alexandre Bourgeois Philippe A Guy Marc Enslen Inge Lise F Nielsen Sunil Kochhar Myriam Richelle Laurent B Fay Gary Williamson

BACKGROUND To our knowledge, there is no direct information on lycopene metabolism in humans. OBJECTIVE The objective of this study was to quantify the long-term human bioavailability of lycopene in plasma and skin after a single dose of (14)C-lycopene and to profile the metabolites formed. DESIGN We preselected 2 male subjects as lycopene absorbers and gave them an oral dose of 10 mg synth...

Journal: :The British journal of nutrition 2003
Yossi Walfisch S Walfisch R Agbaria J Levy Y Sharoni

Lycopene, the main carotenoid found in tomatoes and tomato-based products, has been reported to be protective against several types of cancer. Assessment of changes in plasma concentration of carotenoids following ingestion of lycopene-rich food sources does not necessarily predict changes in lycopene concentration or distribution of its isomers in other body tissues. Our aim was to determine t...

Journal: :Journal of environmental biology 2009
Kultigin Cavusoglu Emine Yalcin

The present study was carried out to evaluate the radioprotective role of lycopene on chromosomal aberrations (CAs) induced by gamma (gamma) radiation in human lymphocytes. For this purpose, we used in vitro dose-effect relationship, and correlate these data with statistical parameters. CAs were evaluated in terms of chromosome break, dicentric, tricentric, acentric, fragment and ring. Mitotic ...

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