Novel digital technologies always lead to high density and very low power consumption. One of these concepts is Quantum-dot Cellular Automata (QCA), which is one of the new emerging nanotechnology-based on Coulomb repulsion. This article presents three architectures of logical “XOR” gate, a novel structure of two inputs “XOR” gate, which is used as a module to implement four inputs “XOR” gate a...

Xanthine oxidoreductase (XOR) is the rate-limiting enzyme in purine catabolism occurring in most cell types. However, this housekeeping gene is expressed at very high levels in a number of mammalian tissues including the lactating mammary epithelium, suggesting additional roles for XOR in these tissues. Mice with targeted disruption of XOR were generated to assess these potential additional rol...

Modern conflict-driven clause learning (CDCL) SAT solvers are very good in solving conjunctive normal form (CNF) formulas. However, some application problems involve lots of parity (xor) constraints which are not necessarily efficiently handled if translated into CNF. This paper studies solving CNF formulas augmented with xor-clauses in the DPLL(XOR) framework where a CDCL SAT solver is coupled...

The housekeeping enzyme xanthine oxidoreductase (XOR) has been studied intensively over the past 100 years, yet the complexity of its in vivo function is still poorly understood. A large body of literature focuses on the different catalytic forms of XOR and their importance in the synthesis of reactive oxygen and reactive nitrogen species, which are involved in many disease processes. More rece...

Recent universal-hashing based approaches to sampling and counting crucially depend on the runtime performance of SAT solvers on formulas expressed as the conjunction of both CNF constraints and variable-width XOR constraints (known as CNF-XOR formulas). In this paper, we present the first study of the runtime behavior of SAT solvers equipped with XOR-reasoning techniques on random CNF-XOR form...

Upregulation of xanthine oxidoreductase (XOR) increases vascular reactive oxygen species (ROS) levels and contributes to nitroso-redox imbalance. However, XOR can generate nitric oxide (NO) from nitrite, and increased superoxide could inactivate NO formed from nitrite. This study tested the hypothesis that XOR contributes to the cardiovascular effects of nitrite in renovascular hypertension, an...

Ever since lightweight cryptography emerged as one of the trending topics in symmetric key cryptography, optimizing implementation cost MDS matrices has been center attention. In this direction, various metrics like d-XOR, s-XOR and g-XOR have proposed to mimic hardware cost. Consequently, efforts also made search for optimal dimensions relevant cryptographic applications according these metric...

Loss of xanthine oxidoreductase (XOR) has been linked to aggressive breast cancer in vivo and to breast cancer cell aggressiveness in vitro. In the present study, we hypothesized that the contribution of XOR to the development of the normal mammary gland may underlie its capacity to modulate breast cancer. We contrasted in vitro and in vivo developmental systems by differentiation marker and mi...

OBJECTIVE Hyperuricemia is common in patients with metabolic syndrome. We investigated the role of xanthine oxidoreductase (XOR) in atherosclerosis development, and the effects of the XOR inhibitor allopurinol on this process. METHODS AND RESULTS Oral administration of allopurinol to ApoE knockout mice markedly ameliorated lipid accumulation and calcification in the aorta and aortic root. In ...

BACKGROUND Xanthine oxidoreductase (XOR) is involved in oxidative metabolism of purines and is a source of reactive oxygen species (ROS). As such, XOR has been implicated in oxidant-mediated injury in multiple cardiopulmonary diseases. XOR enzyme activity is regulated, in part, via a phosphorylation-dependent, post-translational mechanism, although the kinase(s) responsible for such hyperactiva...