نتایج جستجو برای: xenograft model

تعداد نتایج: 2117815  

Journal: :iranian endodontic journal 0
arash khojasteh assistant professor, director of basic science research, department of oral and maxillofacial surgery, dental research center, faculty of dentistry, shahid beheshti university of medical science, tehran, iran mohammad hossein ghahremani associate professor, department of pharmacology and toxicology, faculty of pharmacy, tehran university of medical sciences, tehran, iran seyed nasser ostad professor, department of pharmacology and toxicology, faculty of pharmacy, tehran university of medical sciences, tehran, iran mohammad eslami professor, department of oral and maxillofacial pathology, tehran university of medical sciences, tehran, iran pourya motahhary golnaz morad dental research center, shahid beheshti university of medical science

introduction : deproteinized bovine bone mineral (bio-oss) is a xenogenic bone substitute, widely used in maxillofacial bone regeneration. the aim of this in vitro study was to investigate its influence on the growth behavior of human osteosarcoma cell line, saos-2 culture, and compare it with the physiologic dose of dexamethasone, an inductive factor for osteoblasts. materials and methods: hum...

2012
Chen Hua Dong Jun

In the life sciences, scientists are paying more and more attention to the human brain, the essential center of the body. The gliomas in human brains are especially unique challenges for doctors due to the difficulties of identifying early cancer lesions and little effective treatments. Gliomas account for about half of the central nervous system tumors. Due to its invasive growth and other mal...

Journal: :Bio-protocol 2017
Hsin-Wei Liao Mien-Chie Hung

The host microenvironment plays a prominent role in tumor growth, angiogenesis, invasion, metastasis, and response to therapy. Orthotopic tumor model mimics the natural environment of tumor development and provides an effective approach to investigate tumor pathophysiology and develop therapeutic strategies. This protocol describes the technique involving injection of colorectal cancer cell sus...

Journal: :Anticancer research 2013
Makoto Moriyama Yutaka Shimada Takuya Nagata Tetsuya Omura Shinichi Sekine Koshi Matsui Isaku Yoshioka Tomoyuki Okumura Shigeaki Sawada Toru Yoshida Kazuhiro Tsukada

BACKGROUND The clinical outcome of gastrointestinal stromal tumor (GIST) has been improved by the introduction of molecular-targeting drugs. However, resistance to these drugs appears during the course of treatment. The aim of this study was to establish and characterize a human xenograft model of GIST. MATERIALS AND METHODS GIST tissue from a patient with esophageal GIST was implanted under ...

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