Xanthan gum (15 g/d) was given for 10 d to eighteen normal volunteers. In vivo measurements of stool output, transit time, frequency of defaecation and flatulence were compared with a preceding control period of 10 d. At the end of the control and test periods fresh faecal homogenate from each subject was anaerobically incubated with xanthan gum and control solutions to assess the ability of th...

xanthan gum is an extracellular polysaccharide produced by various xanthomonas species such as x. campestris . the objective of present study was to investigate the influence of different carbon and nitrogen sources on xanthan gum production by x. campestris . using an experimental response surface methodology (rsm) complemented with a central composite design (ccd), the impact of peptone, lact...

An oscillating capillary rheometer was used to investigate the dynamic viscoelastic and intrinsic viscosity properties of deacetylated xanthan (0.025%), native xanthan (0.025%), guar gum (0.075%), and xanthan–guar mixtures in dilute solutions. Influence of ionic strength on xanthan conformation and interaction with guar gum was elaborated. As the salt concentration increased, a significant (P <...

Background Xanthan gum, a commercial microbial polysaccharide, has many industrial applications, including the tertiary recovery of oil, due to its unique rheological behavior (e. g. high viscosity at low concentrations, pseudoplasticity, solubility, stability over a wide range of pH values and temperatures, compatibility with many salts) [1]. Its production employs glucose or sucrose, which ra...

The present study was undertaken to develop oral sustained release tablets of metoprolol tartrate using natural hydrophilic matrix formers (xanthan gum and tragacanth). Sustained release matrix tablets of metoprolol tartrate were prepared by using different ratios of drug, xanthan gum and tragacanth. Microcrystalline cellulose (MCC) was used as diluent. The polymer was incorporated into a matri...

Xanthan gum is a microbial polysaccharide of great commercial significance. This review focuses on various aspects of xanthan production, including the producing organism Xanthomonas campestris, the kinetics of growth and production, the downstream recovery of the polysaccharide, and the solution properties of xanthan.

Polysaccharide-polysaccharide interactions are attractive in the food, polymer and pharmaceutical systems because they may impart novel or improved functional properties to products and reduce costs. In this work, the rheological interaction of sage seed gum (SSG) as a novel hydrocolloid with xanthan gum (XG) was studied in the dilute region. The intrinsic viscosity of the XG-SSG mixture at fiv...

The purpose of this research was to develop gastro-retentive delivery system of atenolol which, after oral administration should have the ability to prolong gastric residence time with desired in vitro release profile. Atenolol was chosen as a model drug because it is poorly absorbed from the lower gastrointestinal tract. The tablets were prepared by direct compression technique, using natural ...

Xanthan gum is exo-polysaccharide, produced by Xanthomonas campestris. Considering a reactor operating in continuous mode, optimum dilution rate is determined by maximization condition. Optimum dilution rate is the dilution rate at which the productivity of xanthan gum is maximum. The current work is focused on implementing an algorithm for design of reactor, having optimum dilution rate as the...

An extracellular cell lytic enzyme from Pseudomonas sp. was active on heat killed cells of Xanthomonas campestris. The lytic activity caused enzymatic digestion of X.campestris xanthan gum. Digestion was effective for highly viscous native xanthan 2.0% (w/v) and 2.5% (w/v) commercial Sigma xanthan. Scanning electron microscopy and SDS-PAGE observations confirmed the cell lytic action on X.campe...