wound healing has always been among important and crucial subjects in medicine. morphine dependency has also been a social and health problem in the middle east. this study was aimed to investigate the effects of morphine dependency on pro-inflammatory and fibroblast cell recruitment, as well as re-epithelialization and the revascularization processes involved in secondary intention wound heali...

conclusions stem cell therapies in wound care may lessen the morbidities associated with wound healing. an ideal method for the effective administration of stem cells for burn patients has not yet been elucidated. further comparison of the local and systemic effects in burn patients, associated with each route of stem cell delivery, needs to be performed. results application of cells to the bur...

introduction: different modalities have been used to achieve better results in wound healing among which are laser and pharmacological agents. to our knowledge, there is no investigation to compare phenytoin and laser together. in this study, we aimed to evaluate laser and phenytoin efficacy and compare their effect on wound healing. methods: we used 60 rats. the animals were divided into 4 gro...

surgical wound infections are usually encountered due to the endogenous rather than the exogenousinfective sources. the objective of this study was to evaluate the effect of a distant inoculated infective source on the contamination of surgical wounds. thirty white new zealand rabbits divided randomly into three control and three treatment equal groups. in treatment groups 24 hrs before surgica...

Despite the prevalence of different kinds of wounds among people around the world, challenges ahead for managing wound healing continues. One of the most important issues for wound healing is infection that can delay healing process. Also, drug-resistant infections are growing as a worrying challenge in medicine. A lot of studies done over different methods to improve wound healing process, whi...

abstract background: pressure ulcer is one of the main concerns of nurses in medical centers around the world, which, if untreated, causes irreparable problems for patients. in recent years, nitric oxide (no) has been proposed as an effective method for wound healing. this study was conducted to determine the effect of nitric oxide on pressure ulcer healing. materials and methods: in this clini...

objective: to assess the effects of platelet rich plasma (prp) with chitosan biodegradable film on full thickness wound healing in rat. methods: this was an experimental study being performed in 2015 during a 4-month period. twenty-four male white wistar rats were divided into four groups of 12 rats each, randomly: control group (sham) with creation of wounds and no treatment, prp group with cr...

background: this study was designed to investigate the efficacy of pentoxifylline (ptx) in the treatment of irradiated wounds. materials and methods: ten female pigs of the large white strain were used in these investigations. six skin fields, 4 * 4 cm and separated from each other by 4 cm, were marked out on each flank and those on left flank were irradiated with 18gy single dose of 250 kv x-r...

In the present investigation, methanolic extract of Mimusops elengi  leaves were evaluated for wound healing activity. Entire wound healing process is complex series of events that begins at the moment of injury and can continue for months to years. Methanolic extract of Mimusops elengi leaves were examined for wound healing activity in the form of ointment by the excision, the incision and ...

the effect of prepared ayurvedic formulation was evaluated on excision and incision wound models in rats. the wound-healing activity was assessed by the rate of period of epithelialization and skin-breaking strength. histological study of the granulation tissue was carried out to know the extent of collagen formation in the wound tissue. the ayurvedic formulation prepared was then promoted for ...