Severe cardiac and neurologic toxicities of tricyclic antidepressant (TCA) overdose have been reported since the introduction of TCAs in 1950s. Despite the decreased numbers of TCA overdoses, the mortality and morbidity rates of TCA overdose have remained constantly high. Clinical manifestations of TCA overdose are characterized by unconsciousness and specific electrocardiography (ECG) abnormal...

acute yew (taxus baccata) intoxication was induced in 7 adult sheep by oral administration of the plant materials at the dose of 2.5g/kg body weight. blood samples for hematology and serum biochemistry were collected before and after the induced intoxication.electrocardiography was performed using a base-apex lead. intoxicated animals displayed lethargy, depression, bradycardia and varying inte...

We report the case of a patient who had development of ventricular fibrillation following rapid intravenous administration of magnesium sulfate (2 g over 5 s) for treatment of sustained monomorphic ventricular tachycardia. Initial slowing of the tachycardia was followed by gradual widening of QRS complexes and electrical alternans, leading to ventricular fibrillation within 3 min of magnesium a...

Aim: Frequent premature ventricular contractions (PVCs) can cause impaired function or dilatation of cavities. The frontal plane QRS-T [f(QRS-T)] angle is an indicator instability in the electrophysiological properties myocardium and associated with arrhythmias. present study aimed to investigate whether f(QRS-T) angle, as a marker repolarization heterogeneity, predicts contraction burden ambul...

To facilitate the explanation of Fig. 1, the QRS complexes are labelled. The first two show a normal QRS preceded by a normal PR interval. Thereafter the QRS configuration changes. Complexes 3 to 6 show gradual widening, a frontal axis shift to horizontal and loss of the initial q in leads I and V6, an rS pattern in lead III, and the development of a left bundle branch block-like QRS configurat...

Simultaneous ischemia in two myocardial regions is a potentially lethal clinical condition often unrecognized whose corresponding electrocardiographic (ECG) patterns have not yet been characterized. Thus, this study aimed to determine the QRS complex and ST-segment changes induced by concurrent ischemia in different myocardial regions elicited by combined double occlusion of the three main coro...

Ventricular arrhythmias due to ARVD and right ventricular outflow tract arrhythmia (RVOTA) share the same left bundle branch block pattern with inferior axis on the ECG. The former has a more malignant course while the latter has a better prognosis and is more amenable to radiofrequency catheter ablation. Hence differentiating them is of utmost clinical importance in the management of these pat...