نتایج جستجو برای: wide hybridization
تعداد نتایج: 413034 فیلتر نتایج به سال:
Introduction: Lots of human diseases and syndromes result from partial or complete gene deletions and duplications or changes of certain specific chromosomal sequences. Many various methods are used to study the chromosomal aberrations including Comparative Genomic Hybridization (CGH), Fluorescent in Situ Hybridization (FISH), Southern blots, Multiplex Amplifiable Probe Hybridisation (MAP...
Introgression is the movement of genes or gene flow from one species into the gene pool. wide hybridisation breaks the species barrier for gene transfer and makes it possible to transfer the genome of one species to other, which results alteration in genotypes and phenotypes of the progeny. The main objective of wide hybridisation is to transfer desirable genes, to create genetic variability wh...
High-density oligonucleotide arrays are powerful tools for the analysis of genome-wide expression of genes and for genome-wide screens of genetic variation in living organisms. One of the critical problems in high-density oligonucleotide arrays is how to identify the actual amounts of a transcript due to noise and cross-hybridization involved in the observed signal intensities. Although mismatc...
Microarray-based pooled DNA methods overcome the cost bottleneck of simultaneously genotyping more than 100 000 markers for numerous study individuals. The success of such methods relies on the proper adjustment of preferential amplification/hybridization to ensure accurate and reliable allele frequency estimation. We performed a hybridization-based genome-wide single nucleotide polymorphisms (...
Natural interspecific hybridization has been observed in a diverse array of taxa [1-3], and the production of such hybrids can have a wide range of evolutionary consequences. For instance, natural hybridization can act as a ‘destructive’ force, resulting in the fusion of taxa that do not reveal strong reproductive isolation [1]. Alternatively, it can result in evolutionary novelty via the produ...
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