نتایج جستجو برای: wedelolactone
تعداد نتایج: 73 فیلتر نتایج به سال:
Medicinal herbs are well known and studied over the past millennia in most of developing countries as a rational means treatment against various diseases disorders. Wedelolactone (WDL), major bioactive compound Eclipta prostrata L (Eclipta alba L), has been reported with potential benefits human health chronic diseases. However, comprehensive study on WDL pharmacological ailments, to best our k...
Methamphetamine (METH) is an extremely addictive stimulant drug that is widely used with high potential of abuse. Previous studies have shown that METH exposure damages the nervous system, especially dopaminergic neurons. However, the exact molecular mechanisms of METH-induced neurotoxicity remain unclear. We hypothesized that caspase-11 is involved in METH-induced neuronal apoptosis. We tested...
Oxidative stress, including Ultraviolet (UV) irradiation-induced skin damage, is involved in numerous diseases. This study demonstrates that water extract of Eclipta prostrata L. (WEP) has a potent effect in scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide radicals, and chelating ferrous ion, exhibiting IC50 values of 0.23 mg/mL, 0.48 mg/mL, and 1.25 mg/mL, respectively. The WEP tota...
Oxidative stress and Ultraviolet (UV) irradiation-induced skin damage, is involved in numerous diseases. Eclipta alba which belongs to Asteraceae family is used traditionally in Ayurvedic system of medicine in India for the treatment of liver diseases. Our study shows that water extract of E. alba has a potent effect in scavenging 1, 1-diphenyl-2-picrylhydrazyl (DPPH), chelating ferrous ion, an...
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