Background Campylobacter jejuni is considered as a chicken commensal. The gut microbiota and the immune status of the host may affect its colonization. Infectious bursal disease virus (IBDV) is an immunosuppressive virus of chickens, which allows secondary pathogens to invade or exacerbates their pathogenesis. To investigate the effect of IBDV-induced immunosuppression on the pathogenesis of C....

BACKGROUND Infectious bursal disease virus (IBDV) is a pathogen of worldwide significance to the poultry industry. IBDV has a bi-segmented double-stranded RNA genome. Segments A and B encode the capsid, ribonucleoprotein and non-structural proteins, or the virus polymerase (RdRp), respectively. Since the late eighties, very virulent (vv) IBDV strains have emerged in Europe inducing up to 60% mo...

A reverse transcriptase polymerase chain reaction restriction fragment length polymorphism (RT-PCR/RFLP) technique was used for the identification and characterization of Pakistani field isolates of infectious bursal disease virus (IBDV). A total of 8 bursa samples were collected from two outbreaks during September and October 2003 from Tehsil Sumandri, Dist. Faisalabad with 40-50% mortality in...

Quality control tests were applied to prove the efficacy of the Vaxxitek HVT+IBD vaccine by Identity, sterility, titration, immunosuppression, safety and potency tests. Vaxxitek HVT+IBD vaccine proved to be safe when inoculated in 1-day old chicks free from maternal derived antibodies, broiler chicks and Swiss mice with 10field dose of the vaccine. The Vaxxitek HVT+IBD vaccine did not interfere...

Aim: Characterization of Infectious bursal disease viruses (IBDV) from the two outbreaks in Jos Nigeria, using reverse transcriptase polymerase chain reaction/restriction fragment length polymorphism (RT-PCR/RFLP) technique. Materials and Methods: A total of 40 bursa samples were collected from two outbreaks in November 2011 from two farms of 6-8 weeks old pullets within Jos South Local Governm...

Ten infectious bursal disease virus (IBDV) field strains were isolated from 15 broiler flocks located in various parts of Asyut, Egypt. Seven strains were subjected to comparative sequencing and phylogenetic analyses to help provide optimal control program for protection against IBDV infection. Sequence analysis of a 530 bp hypervariable region in the VP2 gene revealed that the rate of identity...

BACKGROUND This study aimed at investigating a potential effect caused by coccidia on the immune response to vaccine- and very virulent infectious bursal disease virus (vvIBDV) in SPF chickens. METHODS Two groups of three weeks old SPF chickens were vaccinated prior to inoculation with coccidia and challenge with virulent IBDV, all within a period of eight days. Two control groups were simila...

In this study, immunohistochemistry was used to clarify the early stages of viral kinetics and cycliccourse of IBDV, IR499, which has been described earlier as a very virulent strain (vvIBDV). Fifteen, 4-week-old SPF chickens were inoculated with 10³ EID50 of vvIBDV, IR499, via oculo/nasal route. Five birdsserved as controls, and inoculated with phosphate buffered saline (PBS). The birds were t...

BACKGROUND Infectious bursal disease is a highly contagious and acute viral disease caused by the infectious bursal disease virus (IBDV); it affects all major poultry producing areas of the world. The current study was designed to rigorously measure the global phylogeographic dynamics of IBDV strains to gain insight into viral population expansion as well as the emergence, spread and pattern of...

Vaccination is an essential component in controlling infectious bursal disease (IBD), however, there a lack of information on the genetic characteristics recent virus (IBDV) that was isolated from IBD vaccinated commercial flocks Malaysia. The present study investigated 11 IBDV isolates were poultry farms. detected using reverse transcription-polymerase chain reaction (RT-PCR) targeting hyperva...