OBJECTIVE: Screening siblings of index patients with vesicoureteral reflux (VUR) has been proposed to identify children who are at risk for renal damage. However, screening siblings for VUR remains controversial. We investigated the prevalence of VUR and renal cortical abnormalities in the sibling population in a large cohort of families with VUR. METHODS: Between 1998 and 2012, parents of inde...

Introduction: Micturating cystourethrogram (MCUG) is the gold standard test for diagnosis of vesicoureteric reflux (VUR). The study aims to establish association between presence VUR and renal outcomes. Methods: A cross-sectional retrospective was conducted in children who were referred MCUG at a tertiary centre over 10-year period. Baseline characteristic data results ultrasound, MCUG, with fu...

BACKGROUND Approaches to the management of vesicoureteral reflux (VUR) in children have changed rapidly in recent years. Multiple studies published over the last decade have contributed to these changes by challenging the dogma that all children with reflux require and benefit from continuous antibiotic prophylaxis. The advent and wide acceptance of endoscopic treatment for VUR has also contrib...

OBJECTIVE: Screening siblings of index patients with vesicoureteral reflux (VUR) has been proposed to identify children who are at risk for renal damage. However, screening siblings for VUR remains controversial. We investigated the prevalence of VUR and renal cortical abnormalities in the sibling population in a large cohort of families with VUR. METHODS: Between 1998 and 2012, parents of inde...

INTRODUCTION Vesicoureteral reflux (VUR) occurs in 20-50% of children suffering from recurrent urinary tract infections (UTIs) and is associated with an increased risk of renal scarring and impaired renal function. Early detection of renal perfusion deterioration would allow for the implementation of more aggressive treatment and potentially prevent further damage to the renal parenchyma. The a...

Background: Experience with vesicoureteral reflux (VUR) differs in different centers and there is plenty of controversies. Objective: To evaluate the outcome of primary VUR complications and the rate of recurrence of UTI. Methods: In a retrospective study, the medical charts of all infants and children with primary VUR who were followed up by one nephrologist were reviewed. During 16 years, 271...

BACKGROUND Little generalizable information is available on the outcomes of children diagnosed with bladder and bowel dysfunction (BBD) after a urinary tract infection (UTI). Our objectives were to describe the clinical characteristics of children with BBD and to examine the effects of BBD on patient outcomes in children with and without vesicoureteral reflux (VUR). METHODS We combined data f...

Purpose: We studied the inheritance pattern, clinical features and outcome in children with vesicoureteral reflux (VUR). Characteristics of known familial VUR cases were also compared with those of sporadic VUR. Material and Methods: 726 patients were treated for VUR between 19902004. The families were contacted by letter inquiring if other members of the family were affected. The phenotype of ...

OBJECTIVE To evaluate the accuracy of an acute (99m)Tc-dimercaptosuccinic acid (DMSA) scan in predicting dilating vesicoureteral reflux (VUR) among young children with a febrile urinary tract infection (UTI). METHODS The medical records of children (≤ 2 years of age), presenting with febrile UTI between January 2000 and December 2011, were retrospectively reviewed. RESULTS A total of 523 ch...

BACKGROUND Experience with vesicoureteral reflux (VUR) differs in different centers and there are plenty of controversies. OBJECTIVE The aim of this study was to evaluate the outcome of primary VUR complications and the rate of recurrence of UTI. METHODS The medical charts of all infants and children with primary VUR who were followed up by two nephrologist were reviewed. During 19 years (1...