13 Running title-de novo design of novel antimicrobial peptides 14 Abstract 21 Increased microbial drug resistance has generated a global requirement for new anti 22 infective agents. As part of an effort to develop new, low molecular mass peptide 23 antibiotics we used a rationale based minimalist approach to design short, non hemolytic, 24 potent and broad spectrum antibiotic peptides with in...

This experimental investigation of calcite growth quantifies relationships between solution supersaturation and the rates of step advancement. Using in situ fluid cell atomic force microscopy (AFM), we show that the movement of monomolecular steps comprising growth hillocks on {101#4} faces during the growth of this anisotropic material is specific to crystallographic direction. By quantifying ...

The development and testing of an observational gait assessment instrument, the Spinal Cord Injury Functional Ambulation Inventory (SCI-FAI) is described. To assess validity and reliability, 22 subjects with incomplete spinal cord injury were scored by four raters. Raters scored each subject three times, once live (LS) and twice from videotaped records (VS1, VS2). A moderate-good negative corre...

Cryopreservation of ovarian tissue has been studied for female germline preservation of farm animals and endangered mammalian species. However, there are relatively few reports on cryopreservation of fish ovarian tissue and especially using vitrification approach. Previous studies of our group has shown that the use of a metal container for the cryopreservation of bovine ovarian fragments resul...

BACKGROUND In the lower Mekong Basin and coastal zones of Southern Vietnam, forests dominated by the genus Melaleuca have two notable features: most have been substantially disturbed by human activity and can now be considered as degraded forests; and most are subject to acute pressures from climate change, particularly in regards to changes in the hydrological and sodicity properties of forest...

Rodents move their whiskers to locate and identify objects. Cortical areas involved in vibrissal somatosensation and sensorimotor integration include the vibrissal area of the primary motor cortex (vM1), primary somatosensory cortex (vS1; barrel cortex), and secondary somatosensory cortex (S2). We mapped local excitatory pathways in each area across all cortical layers using glutamate uncaging ...

For a long period of time, design and manufacturing technology of high flow rated vertically suspended pumps (VSPs) which have an extensive applications in many industries such as water and wastewater, mining, petrochemical and oil and gas industries, used to be imported from European countries. For the first time in Iran's pump industry, with the support of Ministry of Petrochemical[ah1]  and ...