Volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) are commonly used treatment techniques for cancer treatment, and both the VMAT and IMRT techniques use the photon beam (mega-voltage X-rays) to deliver radiation dose to the tumor. The capability of modulating radiation beam has increased the ability of delivering more conformal dose distributions to tumor ...

The purpose of this study was to compare International Commission on Radiation Units and Measurements (ICRU, report 38) reference points, used in conventional brachytherapy planning, with Computed Tomography (CT)-based volumetric calculations of radiation doses for target volumes and organs at risk in biopsy-proven cervix carcinoma patients. All patients underwent brachytherapy using CT-compati...

External beam radiation therapy is concerned with the precise and accurate delivery of radiation for cancer treatment. Highly-collimated beams are generated in a linear accelerator, consisting of several hardware components that move around the patient in a complex geometry to allow radiation target the tumor from every possible angle. The complex arrangements of the hardware components may giv...

Introduction:   Radiotherapy with or without surgery plays an important role in the treatment of patients with esophageal cancer. In the treatment planning of esophageal cancer, usually normal lung volume was observed in the treatment fields and probably received high radiation dose. The incidence of radiation pneumonitis (RP) after radiotherapy (RT) for sensitive organ of lu...

OBJECTIVES The diagnosis of root fractures by conventional radiographs is still difficult because of limitations of 2D images. Cone-beam volumetric tomography improves the diagnosis capacity in dentistry, such as increased radiation dose to the patient and presence of artifacts on the image. STUDY DESIGN This study compared the images obtained on conventional periapical radiographs and 3D sca...

Radiation therapy has been one of the major treatment modalities for the prostate cancer over the past few decades. Treatment planning system (TPS) is an integral component in radiation therapy in order to ensure the accurate estimation of radiation dose to the tumor. However, due to the variability in optimization techniques and beam modeling among various TPS, the current literature on radiat...

Background: Sinonasal cancer (SNC) arises in the proximity of many critical organs at risk (OAR). Therefore, minimizing radiation doses to critical organs is a priority. We evaluated the use of a fast, non-coplanar volumetric arc therapy (VMAT) delivery technique for this purpose.

Gene therapy combined with radiation therapy to enhance selectively radiation cytotoxicity in malignant cells represents a new approach for cancer treatment. We investigated the efficacy of adenoviral (Ad5)-directed cytosine deaminase/5-fluorocytosine (CD/5-FC) enzyme/prodrug gene therapy to enhance selectively the tumoricidal action of ionizing radiation in human cancer xenografts derived from...