Quinolone antibacterial agents are currently used for the treatment of various bacterial infections. The nature of functional group at the 7 position of the quinolone ring system is known to have strong influence on the spectrum and extent of in vitro antibacterial activity. Accordingly, a series of N-L2- oxo-2-(2- furyl) and N-[2- oxyimino (2- furyl) ethyl] piperazinyl quinolone derivatives...

the presence of antibacterial activity in bovine β-lactoglobulin and in α-lactalbumin hydrolysates was investigated. the plasmin-digest of β-lactoglobulin (pdβ) and of α-lactalbumin (pdα) were fractionated, using reversed phase high performance liquid chromatography. the antibacterial activity of β-lactoglobulin, α-lactalbumin, nisin, plasmin, pdβ and pdα were in vitro tested against pathogenic...

OBJECTIVE To investigate the in vitro effects of the antibacterial drugs, meropenem trihydrate, piperacillin sodium, and cefoperazone sodium, on the activity of human serum paraoxonase (hPON1). METHODS hPON1 was purified from human serum using simple chromatographic methods, including DEAE-Sephadex anion exchange and Sephadex G-200 gel filtration chromatography. RESULTS The three antibacter...

A series of 5-thiocarbamate oxazolidinones was prepared and tested for in vitro and in vivo antibacterial activities. The results of in vitro antibacterial activity indicated that the 5-thiocarbamate group was a suitable substituent for the activity by the 5-moderate hydrophilicity. The compounds within a favorable logP value range were found to have potent in vitro antibacterial activity again...

abstract: in a wide search program towards new and efficient antimicrobial agents, a series of 4-substituted-1,2,4-triazolidine-3,5-dione derivatives namely urazoles holding an alkyl moiety at position 4 have been synthesized and tested for their in vitro antibacterial and antifungal activities. the structures of these compounds have been investigated by spectral data. the synthesized compounds...

costus speciosus (koen) j.e. sm. plant and its extracts are used for treatment of fever, snake bites, jaundice, and as a purgative, astringent and antibacterial agent. in the present study, an attempt has been made to evaluate in vitro antioxidant activity of different extracts of this plant by dpph radical scavenging activity, total antioxidant capacity, nitric oxide scavenging activity, ion c...

objective: in this study, antimicrobial activities of an ethanol extract of tribulus terrestris aloneand in combination with capsella bursa-pastoris and glycyrrhiza glabra were examined in vitro against six pathogens namely streptococcus mutans, streptococcus sanguis, actinomyces viscosus, enterococcus faecalis staphylococcus aureus, and escherichia coli. materials and methods: antibacterial ac...

Abstract Introduction: The aim of this study was to identify the antibacterial components in the ethanol extraction of Aloe vera against four clinically frequent pathogenic  bacteria. Materials and Methods: In this in-vitro study, Aloe vera extraction was prepared by dissolving 500 grams of the powder in 5L of 95% ethanol. The antibacterial activity of the extraction against Staphylococcus a...

Background and purpose: Antibacterial properties of restorative materials are of great advantage as they control the progression of tooth decay. The use of self-adhesive composite materials has some benefits such as easier application and reduced treatment time. Because the antibacterial properties of restorative materials can play an important role in preventing secondary decay, especially in ...