Only a few studies have been reported on the biochemistry of the vitreous body in the developing eye. Bernbridge and Pirie (1) determined the total hexosamine and the total nitrogen content of the filtered vitreous body of rabbits after birth and found that during the first three weeks there was a decrease in both the nitrogen and the hexosamine concentration. Schweer and Siidhof (2) confirmed ...

REVIEWS of some recent literature concerning the biochemistry of the vitreous body contain no references to the presence of enzymes (Bellows, 1952, 1953; von Sallmann, 1953, 1954; McLean, 1954). However, the possibility of the existence of enzymes in the vitreous body has not been overlooked. Lepine (1870) reported that the vitreous of dogs, rabbits, and frogs contained a substance which caused...

The natural vitreous is a transparent, gelatinoid structure occupying four-fifths of the volume of the eye. It has a thin, membrane-like structure corresponding to the vitreous cortex that extends from the ora serrata to the posterior pole.1 It is somewhat spherical but slightly flattened meridionally, and it has a cup-shaped depression in its anterior side. It consists of about 99% water by we...

AN attempt has been made to find the cells of origin and the time of origin during development of the vitreous hyaluronic acid. The adult vitreous body of those species so far examined seems to owe its characteristic jelly-like properties to the presence of small amounts of an insoluble collagen-like protein laid down in fibrous lamellae and a low concentration of hyaluronic acid. Earlier work ...

Imaging the vitreous is an attempt to view what is by design invisible. The inability to adequately image vitreous hinders a more complete understanding of its normal structure and function and how these change in aging and disease. The combined use of more than one technique could provide better imaging for investigational and clinical purposes. Past and present imaging methodologies are summa...

PURPOSE To investigate the possibility of using polylactic acid (PLA) as a surgical adjuvant for visualizing the vitreous body during vitrectomy. METHODS After a core vitrectomy, 1 mL of PLA suspension was injected into the rabbit vitreous in two groups: group A, 2.5% PLA (n = 5), and group B, 1% PLA (n = 9). Vehicle injection instead of PLA was used as a control (group C, n = 5). The clinica...

The transport of fluorescein monoglucuronide, a fluorescent metabolite of fluorescein, from the vitreous was studied. Ten microliter of 1 mM fluorescein monoglucuronide or fluorescein solution was injected into the rabbit vitreous body, and the vitreous concentration was measured every 2 hr. The rate of loss from the vitreous was 0.066 +/- 0.012 (SD)/hour for fluorescein monoglucuronide and 0.2...

THE problem of the structure of the vitreous body has long been debated. According to Duke-Elder (1930), the argument is beset with difficulties over which anatomists have disputed from the earliest times, largely because of the difficulties involved in the interpretation of their observations. Many studies have been undertaken with the microscope on fixed specimens, with the ultramicroscope on...