Alpine ecosystems are seriously threatened by climate change. One of the key mechanisms by which plants can adapt to changing environmental conditions is through evolutionary change. However, we still know little about the evolutionary potential in wild populations of long-lived alpine plants. Here, we investigated heritabilities of phenological traits, leaf size, and performance traits in natu...

The study examine the antioxidant and antimicrobial potential of the ethanolic and aqueous leaf extracts of ten selected Indian medicinal plants namely, Psidium guajava, Mangifera indica, Polyalthia longifolia, Allium cepa, Phyllanthus amarus, Thespesia populnea, Ricinus communis, Physalis angulata, Ixora coccinea, and Vinca rosea using 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) scavenging assay, to...

In continuation of previous research, the anticancer screening formulation herbal syrup Vinca extract was performed. The performed as per reported literature method. cancer on two Human cell lines. These lines were Lung Cancer line A549 and Breast Cell MCF7. found to be devoid properties.

Oral administration of water fraction of alcoholic extract of leaves of Vinca rosea (fam. apocynaeceae) led to marked lowering of blood glucose level in normal and streptozotocin induced diabetic rats. The hypoglycemic effect of the fraction was comparable with that of tolbutamide.

This paper reports on the vinca alkaloid produced by a novel Nigrospora sphaerica isolated from Catharanthus roseus. Through liquid chromatography-mass spectrometry (LCMS), only the crude mycelia extract of this fungus was positive for determination of vinblastine. This vinca alkaloid was then purified by using high-performance liquid chromatography (HPLC) and tested for cytotoxicity activity u...

the hydroalcoholic extracts of dried ligulate florets of calendula officinalis l., dried leaves of plantago major l., and dried aerial parts of vinca major l. were prepared and used as the main active ingredients of two types of anti-anorectal disease ointments and suppositories. benzocaine was used in one of the formulations, while a mixture of belladonna dry extract and ephedrine sulfate was ...

Introduction: Vinca rosea, an important medicinal plant, is well-known for its anticancer properties especially against breast cancer. In this study, we compared the cytotoxic effects of methanolic extracts of the vegetative (young and old leaves) and reproductive (flowers) organs of this plant on a human squamous cell carcinoma using MTT assay. Methods: The cytotoxic effects of Vinca rosea'...

Some hybrids of vinca alkaloids and phomopsin A, linked by a glycine pattern, have been synthesized in one or two steps, by an insertion reaction and shown to inhibit microtubule assembly. These compounds have been elaborated in order to interact with both the "vinca site" and the "peptide site" of the vinca domain in tubulin. Two out of three hybrids are potent inhibitors of microtubules assem...