OBJECTIVE To assess the predictive impact of morphological, haemodynamic, and clinical variables in the management of patients with isolated ventricular septal defect. DESIGN Retrospective analysis of variables by a sophisticated database management system. PATIENTS AND METHODS 263 consecutive patients with isolated ventricular septal defect diagnosed by echocardiography. The morphological ...

T HE CLOSE anatomic relationship of the conduction system of the heart to most ventricular septal defects'-5 makes the occurrence of complete heart block a potential risk in the repair of these lesions. In our experience , when complete heart block has developed , it has often proved to be a serious complication. Although reversion to sinus rhythm occurs in the early postoperative period in man...

holt-oram syndrome is an autosomal dominant disorder, characterised by skeletal abnormalities of the upper limb associated with congenital heart defect, mainly atrial and ventricular septal defects. skeletal defects exclusively affect the upper limbs in the preaxial radial ray distribution and are bilateral and asymmetrical. they range from clinodactyly, absent or digitalised thumb, hypoplastic...

We have previously reported isolated cases of anatomical and functional closure of ventricular septal defects in tricuspid atresia. To study this phenomenon further, clinical, angiographic, and pathological findings in 20 consecutive cases of tricuspid atresia were reviewed. Sixteen cases were found to have normally related great arteries (type I) and 4 had transposition (type II). In 6 of thes...

T HE PROBABILITY that postnatal spontaneous closure of ventricular septal defect occurs with some frequency has been evident to clinicians for a number of years. This postulate is based upon the presence of characteristic murmurs in childhood which disappear with the growth and development of the patient.1-7 Convincing evidence of spontaneous functional closure of ventricular septal defects is ...

Optimal management of coarctation with ventricular septal defect is difficult. Should one treat the coarctation, the ventricular septal defect, or both? This dilemma was investigated by reviewing 39 successive patients, aged less than 4 months, undergoing coarctation repair without pulmonary artery banding. Twelve hospital deaths occurred. Ventricular septal defect size was graded "blind" accor...