A description of healthy and pathological brain dynamics requires an understanding of spatiotemporal patterns of neural activity and characteristics of its propagation between interconnected circuits. However, the structure and modulation of the neural activation maps underlying these patterns and their propagation remain elusive. We investigated effects of β-adrenergic receptor (β-AR) stimulat...

BACKGROUND Cardiac ATP-sensitive K(+) channels have been suggested to contribute to the adaptive physiological response to metabolic challenge after β-adrenoceptor stimulation. However, an increased atrial K(+)-conductance might be expected to be proarrhythmic. We investigated the effect of ATP-sensitive K(+) channel blockade on the electrophysiological responses to β-adrenoceptor-induced metab...

In vivo measurements of maximum voluntary force – velocity show differences to the in vitro tetanic profile, with eccentric forces not increasing much above isometric and tending to decline with increasing lengthening velocity. Using transcutaneous electrical stimulation maximal eccentric torque has been found to be 1.4 times the isometric value and does not drop off at higher eccentric velocit...

This paper presents a new interpretation of the geometry of Triassic alignment of J. Sidi Mahdi –J. Zitoun in Medjerda Valley Plain (Northern Tunisia) based on detailed analysis of gravity and seismic reflection data. The main results of gravity analysis do not show a distinguish gravity anomaly over Triassic evaporites bodies. The positive gravity anomaly seems to be related to the entire stru...

Little information is available concerning the modulation of cardiac function by β-adrenergic agonists in early-stage embryonic mammalian heart. We have examined the effects of isoproterenol (Iso) on the spontaneous beating rate and action potential (AP) configuration in embryonic mouse hearts at 9.5 days postcoitum (dpc), just 1 day after they started to beat. Iso (3 μM) increased the spontane...

A new model for turbulent flame velocity of premixed flame in spark ignition engine for Iso-octane air mixture has been developed and validated for a wide range of engine operating parameters. The model developed is a zero dimensional thermodynamic model. The effects of engine speed (600-1160 rpm), equivalence ratio (0.7-1.1), unburnt mixture temperature (532650 Rankine), compression ratio (5-8...

Although the main biological hypothesis on the pathophysiology of obsessive-compulsive disorder (OCD) is centered on the serotonin system, indications are available that other neurotransmitters, and even second messengers, particularly the cyclic adenosine monophosphate (cAMP) signaling, may be involved, though effective data are few. Therefore, the aim of the present study was to evaluate and ...