Background VEGF gene has been reported to be related with many diseases and recurrent pregnancy loss in various studies. VEGF polymorphisms are risk factors for pregnancy losses, and generally studies report only women’s genetic analyses. To evaluate the association between VEGF A C405G, C460T, C936T and C2578A polymorphisms and spontaneous abortion, we studied the genotypes of spontaneously a...

objective(s): progestrone is a prequisite for pre-implantation angiogenesis and induce decidual angiogenesis. it is unknown the effect of progestrone administration on the endometrium of hyperstimulated mice at pre-implantation time. material and methods: adult female nmri mice were divided in three groups [control group, ovarian stimulated group and progestrone treated mice after ovarian stimu...

Endometriosis is a debilitating disorder, defined as the presence of endometrial gland and stroma outside of the uterus. It may affect angiogenesis and vascular endothelial growth factor (VEGF) is one of the angiogenic factors that plays an important role in both physiological and pathological angiogenesis. The present study aimed to evaluate the association of VEGF -2549 insertion/deletion (I/...

Background: Nanotechnology symbolizes a broad discipline with enormous potential in cancer treatment bridging one of the bottlenecks traditional approaches therapy which is an inability to deliver adequate quantities anti-cancer drugs tumor area. Studies on nanoparticles indicate their importance angiogenesis and metastasis. Aim: The present study assessed anti-angiogenesis anti-metastatic effe...

Background: Recent discoveries have indicated that, in the developing heart, sinus venosus and endocardium provide major sources of endothelium for coronary vessel growth that supports expanding myocardium. Here we set out to study origin vessels develop response vascular endothelial factor B (VEGF-B) heart effect VEGF-B on recovery from myocardial infarction. Methods: We used mice rats express...

Background: Mesenchymal stem cells (MSCs) are multipotent that can differentiate into several cell types including chondrocytes and osteocytes. The process of differentiation such tissues is aided by transcription factors collagen gene markers. Collagen biosynthesis influenced the presence vascular endothelial growth factor (VEGF) ascorbic acid cofactors prolyl hydroxylase 2 (PHD2) enzyme found...

vascular endothelial growth factor (vegf) is a multifunctional cytokine with distinct functions in angiogenesis, lymphangiogenesis, vascular permeability, and hematopoiesis. vegf is a highly conserved, disulfide-bonded dimeric glycoprotein of 34 to 45 kda produced by several cell types including fibroblasts, neutrophils, endothelial cells, and peripheral blood mononuclear cells, particularly t ...

Title: DNA SEQUENCE VARIATION IN THE PROMOTER REGION OF THE VEGF GENE: IMPACTS ON VEGF GENE EXPRESSION AND MAXIMAL OXYGEN CONSUMPTION Steven John Prior, Ph.D., 2005 Directed By: Assistant Professor Stephen M. Roth, Department of Kinesiology Maximal oxygen consumption (Vo2max) is inversely associated with cardiovascular and all-cause mortality and is responsive to aerobic exercise training. A po...