Thalidomide (THD) exhibits antitumor effects in several types of cancer. However, the failure of THD to inhibit tumor growth has also been observed in a number of murine models in vivo. The mechanism involved in the therapeutic failure of THD remains unclear. The present study demonstrated that, accompanied by growth-arresting and apoptosis-inducing effects (P<0.05), THD upregulated vascular en...

The modification of different zirconium propoxide and hafnium propoxide precursors with 2,2,6,6,-tetramethyl-3,5-heptanedione (Hthd) was investigated by characterization of the isolated modified species. The complexes [Zr(OnPr)3(thd)](2), [Zr(OnPr)(OiPr)2(thd)]2, Zr(OiPr)(thd)3, [Hf(OnPr)3(thd)]2, and Hf(OiPr)(thd)3 were isolated and characterized. The structure of the n-propoxide analogue of Z...

A novel Shape Memory Alloy (SMA) actuator consisting of several thin NiTi bers woven in a counter rotating helical pattern around supporting disks is rst described. This structure accomplishes a highly eecient transformation between force and displacement overcoming the main mechanical drawback of shape memory alloys, that being limited strain. Time domain open loop experiments were then conduc...

Power factor correction (PFC) can be achieved by a single-ended primary inductor converter (SEPIC) operating in boundary conduction mode (BCM) with conventional constant on-time (COT) control, but it is challenging to achieve low total harmonic distortion (THD) and high-power (PF), particularly at high input voltage. A variable (VOT) control strategy for BCM SEPIC PFC without voltage feedforwar...

Fuel cells have been considered as the primary energy source for the distributed power generation as they are highly efficient, modular and clean. The main drawback is that the dc voltage generated by a single fuel cell varies from 0.7V to 1V. Due to the low input voltage in fuel cells, a suitable power conditioner is required to interface to the utility grid or local loads. To meet this requir...

in this paper, the problem of finite time stabilization for guidance system is investigated and a novel nonlinear guidance law against maneuvering targets is proposed based on the principles of parallel navigation. the proposed law is developed using two variable structure control techniques. by applying finite time integral sliding mode and combining it with terminal sliding mode, a new guidan...

Selective harmonics elimination (SHE) is one of the prominent technique that is used to produce required fundamental voltage of multilevel inverters with elimination of selective harmonic orders. The SHE equations are nonlinear equations and are also termed transcendental equations owing to the fact that these equations contain trigonometric terms. Attempt has been made in previous works to sol...