hypothyroidism is usually associated with delayed pubertal development but in rare occasions precocious puberty may ensue which is seen in cases of prolonged and untreated hypothyroidism. this is also called the van wyk grumbach syndrome. here we present 4 cases of precocious puberty due to hypothyroidism.

reaction mechanism among indoline-2,3-dione, pyrrolidine-2-carboxylic acid and (z)-2-(1-(2-hydroxynaphthalen-1-yl)ethylidene)hydroxycarboxamide to form 1’-((((aminooxy)carbonyl)amino)methyl)-2’-(1-hydroxynaphthalen-2-yl)-2’-methyl-1’,2’,5’,6’,7’,7a’-hexahydrospiro[indoline-3,3’-pyrrolo[1,2-a]imidazole-2-one was investigated using density functional theory (dft) at b3lyp basis theory. the three-...

ellis-van creveld syndrome is transmitted as an autosomal recessive trait. this syndrome is accompanied in 60% of cases with congenital heart disease, mostly single atrium or large asd. patients are mostly symptomatic, but in this rare case despite 68 years of age, the patient was free of symptoms except for complete heart block for which pacemaker was inserted

Background: Bacteremia due to Enterococcus faecalis is usually caused by strains resistant to most antibiotics. Effective management of the disease is dependent on rapid detection and characterization of the bacteria, and determination its sensitivity pattern to antimicrobial drugs. The aim of this study was to investigate a more rapid and reliable assay for simultaneous diagnosis of enterococc...

The classical van der Waerden Theorem says that for every every finite set S of natural numbers and every k-coloring of the natural numbers, there is a monochromatic set of the form aS+b for some a > 0 and b ≥ 0. I.e., monochromatism is obtained by a dilation followed by a translation. We investigate the effect of reversing the order of dilation and translation. S has the variant van der Waerde...

fictional names have been one of the most important and serious topics in the contemporary philosophy of language and metaphysics.several questions such as “do fictional names refer to any objects?” “are fictional characters existent objects?” have resulted in a considerable literature of philosophy. in this essay, we will follow two objectives. first we will describe and elaborate the ideas ...

abstract water retention curve (wrc) is a fundamental property of soil. it is used to evaluate available water, permeability, drainage and movement of solutes. despite numerous studies on wrc of soils abroad, no local study has been carried out on charmahal-va-bakhtiari soils. the objective of this study was to compare the quality of fitting of several wrc models to lordegan soils and to select...

an earthquake was happened on 23 october 2011 in van, turkey (mw7.2) at the eastern most area of anatolian plateau and in the neighborhood of iranian border (west azerbaijan province). the study was performed based on field and office observations and has been focused on the process of disaster management in turkey after the 23 october 2011 earthquake. we surveyed the quake from the view point ...