نتایج جستجو برای: valerenic acid
تعداد نتایج: 747444 فیلتر نتایج به سال:
BACKGROUND AND PURPOSE β2/3-subunit-selective modulation of GABAA receptors by valerenic acid (VA) is determined by the presence of transmembrane residue β2/3N265. Currently, it is not known whether β2/3N265 is part of VA's binding pocket or is involved in the transduction pathway of VA's action. The aim of this study was to clarify the localization of VA's binding pocket on GABAA receptors. ...
“Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson’s disease”
The pharmacological activity of neuroactive phytochemicals on recombinant human glutamic acid decarboxylase 65 (hGAD65) was investigated. GAD catalyzes the conversion of glutamic acid to γ -aminobutyric acid (GABA), which acts as an important inhibitory neurotransmitter in the central nervous system (CNS). We describe an improved method in which recombinant hGAD65 was expressed at high levels u...
The use of medicinal plants as an alternative phytotherapeutic remedy against mild illnesses and dysfunctions is increasingly embraced by people. Among these dysfunctions, episodes nervousness anxiety due to lack sleep insomnia are becoming more frequent among the population. To problems, several with sedative activity recommended. In particular, valerian root (Valeriana officinalis L.) most re...
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