BACKGROUND Premature birth is considered one of the main problems in modern Obstetrics. It causes more than 50 % of neonatal mortality; it is responsible for a large proportion of infant morbidity and incurs very high economic costs. Cervical length, which can be accurately measured by ultrasound, has an inverse relationship with the risk of preterm birth. As a result, having an effective inter...

A clinical investigation was undertaken to determine if chemoprophylaxis in the form of a contraceptive pessary would reduce the rate of reinfection with gonorrhoea in 1245 female patients attending a venereal disease clinic. After the introduction of the pessary the reinfection rate over a 16-week period was 19% compared with 40% in the control clinic patients. It was also found that women cou...

BACKGROUND & OBJECTIVES Though nonoxynol-9 (N-9) is available in India as a spermicidal pessary, data on its safety as a potential microbicide among Indian women are not available. Nonoxynol-9 containing compounds have shown anti-HIV activity in in vitro studies and protection against cervical infections. Nonoxynol-9 is being extensively evaluated as a vaginal microbicide world-wide. We assesse...

Two thirds of women opt to use a vaginal pessary initially to manage the symptoms of pelvic organ prolapse. In the UK most women attend a health care professional at least every six months to change the pessary. This represents a significant burden both economically to the health care system and personally for the woman. Annually there are more than 300 appointments for pessary changes at our h...

In vaginal secretions from 16 healthy women aged between 20 and 27 years miconazole persisted in biodetectable concentrations for at least 48 hours after insertion of a single miconazole vaginal pessary. This finding casts doubt on cure rates in vaginal candidosis determined soon after the end of treatment and suggests that current treatment courses with imidazole antifungal agents may be longe...

Objective. We evaluated the use of a one-week ambulatory pessary trial in predicting patients' postoperative outcomes for occult stress incontinence. Methods. Patients with anterior vaginal wall prolapse were offered a pessary trial to predict response to reconstruction. We performed a retrospective review of 4 years of cases. All patients underwent a detailed evaluation including videourodynam...

This report describes a method of estimating the duration of fungicidal activity of amphotericin B in the vagina after its insertion in a cream base. Various localized vaginal infections are treated by the insertion of a pessary or cream into the vagina. This method of treatment is not entirely satisfactory since failure to respond may be due to the method of application rather than to the limi...

Vaginal estrogen cream has widely been used for vaginal atrophy in menopausal women. However, the effectiveness preventing bacterial vaginosis (BV) women with pessary is limited. The study aims to evaluate of uterine prolapse a pessary. A literature search was conducted on PubMed®, Scopus®, and google scholar® before May 2022 using MeSH. Two investigators searched, extracted, appraised evidence...

OBJECTIVE To study the characteristics of pelvic organ prolapse (POP) patients that used a pessary. DESIGN Prospective, descriptive study. SETTING Urogynecology Clinic, Ramathibodi Hospital, Faculty of Medicine, Mahidol University. MATERIAL AND METHOD The authors conducted a prospective, observational study. The average age, parity, average body mass index, menopausal age, pessary type, a...

Cabral Ribeiro J, Leite C. BMJ Case Rep 2017. doi:10.1136/bcr-2017-219690 DESCRIPTION Vaginal pessaries represent a valid therapeutic option for the management of female pelvic organ prolapse in elderly women with significant comorbidities. Although leading to good functional and quality of life outcomes, when neglected, they can cause significant and severe complications. An 87-year-old woman ...