Polylactic acid (PLA) has found widespread use in plastics and in biomedical applications due to its biodegradability into natural benign products. However, PLA-based materials remain limited in usefulness due to difficulty of incorporating functional groups into the polymer backbone. In this paper, we report a strategy for PLA functionalization that establishes the preparation of highly deriva...

Surface modification of titanium dioxide (TiO2) nanoparticle is essential to control its surface properties, thereby to enhance its cell penetration capability, reduce its cytotoxicity, or improve its biocompatibility. In order to graft polyvinyl acetate onto TiO2 nanoparticles, xanthate was chemically immobilized on the surface of TiO2 by acylation followed by nucleophilic substitution with a ...

&gg2g To study HSV reactivation end recurrent disease after comeal transplantation in rats. Methods Female PVG rats were inoculated on the comea with HSV-1 McKrae. At least 4 weeks after inoculation. they received either allogeneic (DA or LEW) or syngeneic corneel grafts end were exemined for stgns of recurrent HSV disease for up lo 30 days. m All allografts wara rejactad. Virus was shed in the...

&gg2g To study HSV reactivation end recurrent disease after comeal transplantation in rats. Methods Female PVG rats were inoculated on the comea with HSV-1 McKrae. At least 4 weeks after inoculation. they received either allogeneic (DA or LEW) or syngeneic corneel grafts end were exemined for stgns of recurrent HSV disease for up lo 30 days. m All allografts wara rejactad. Virus was shed in the...

&gg2g To study HSV reactivation end recurrent disease after comeal transplantation in rats. Methods Female PVG rats were inoculated on the comea with HSV-1 McKrae. At least 4 weeks after inoculation. they received either allogeneic (DA or LEW) or syngeneic corneel grafts end were exemined for stgns of recurrent HSV disease for up lo 30 days. m All allografts wara rejactad. Virus was shed in the...

Layer-by-layer (LbL) assembly of chitosan-graft-phenyl (CHI-g-Ph) and poly(aspartic-graft-octadecyl) chain (PASP-g-OD) with multiple interactions, i.e. electrostatic interaction and hydrophobic interaction, was studied and the growth rate of multilayered films was found to be strongly dependent on the concentration of NaCl in the aqueous solution. LbL assembly of phenyl chitosan-graft-cyclodext...

&gg2g To study HSV reactivation end recurrent disease after comeal transplantation in rats. Methods Female PVG rats were inoculated on the comea with HSV-1 McKrae. At least 4 weeks after inoculation. they received either allogeneic (DA or LEW) or syngeneic corneel grafts end were exemined for stgns of recurrent HSV disease for up lo 30 days. m All allografts wara rejactad. Virus was shed in the...

In a canine model using DLA-identical littermate pairs, we have shown that a regimen of three transfusions of donor blood given 24, 17, and 10 days before transplant uniformly leads to marrow graft rejection, presumably due to sensitization to minor (non-DLA) histocompatibility antigens. Untransfused dogs uniformly achieve sustained engraftment. In the present study, we investigated whether the...