POST-ABORTAL and puerperal infection due to Clostridial organisms have been reported periodically ever since H. M. Little's paper appeared in 1905. Hyperbaric oxygen has been proved to be of great therapeutic value in Clostridial infections (Brummelkamp, Boerema and Hoogendyk, 1963; Brummelkamp, 1964, 1965) but we feel that its use for uterine infections has not been sufficiently emphasised. Si...

POST-ABORTAL and puerperal infection due to Clostridial organisms have been reported periodically ever since H. M. Little's paper appeared in 1905. Hyperbaric oxygen has been proved to be of great therapeutic value in Clostridial infections (Brummelkamp, Boerema and Hoogendyk, 1963; Brummelkamp, 1964, 1965) but we feel that its use for uterine infections has not been sufficiently emphasised. Si...

BACKGROUND Sexual transmission accounts for the majority of HIV-1 infections. In over 75% of cases, infection is initiated by a single variant (transmitted/founder virus). However, the determinants of virus selection during transmission are unknown. Host cell-cell interactions in the mucosa may be critical in regulating susceptibility to infection. We hypothesized in this study that specific im...

Postpartum uterine infections reduce reproductive efficiency and have significant animal welfare and economic consequences. Postpartum uterine infections are classified as nonspecific, but Arcanobacterium pyogenes and Escherichia coli are usually associated with them in cattle and sheep. Pyometra is the most common type of uterine infection in dairy cattle, and it is detected almost exclusively...

UNLABELLED Preterm birth increases the risk of adverse birth outcomes and is the leading cause of neonatal mortality. A significant cause of preterm birth is in utero infection with vaginal microorganisms. These vaginal microorganisms are often recovered from the amniotic fluid of preterm birth cases. A vaginal microorganism frequently associated with preterm birth is group B streptococcus (GBS...

The uterine corpus represents the most common site for tumour development in the female genital system. Uterine neoplasms are categorised as epithelial, mesenchymal, mixed epithelial-mesenchymal or trophoblastic tumours. In this study we employed a mouse genetic approach using the MuLE lentiviral gene regulatory system to functionally test the ability of ecotropic lentiviruses to model epitheli...

Background and Objective: For nearly a century, it has been suspected that reproductive tract infections play an etiologic role in uterine leiomyoma. However, no epidemiologic study of leiomyoma has used the polymerase chain reaction (PCR) to compare uterine tissues from cases and non-cases, and to investigate associations between uterine leiomyoma and infections detected by PC...

We showed earlier that Tritrichomonas foetus-specific bovine immunoglobulin (Ig)G1 and IgA antibodies in uterine and vaginal secretions are correlated with clearance of this sexually transmitted infection. Eosinophils have been noted in previous studies of bovine trichomoniasis but the role of mast cells and IgE responses have not been reported. The hypothesis that IgE and mast cell degranulati...